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22 male reproductive system

22 Male Reproductive System I. Overview. A. Testis (22.1)B. EpididymisC. Ductus deferensD. UrethraE. PenisF. Seminal VesicleG. Prostate. II. Testis. A. Stroma (22.1) 1. tunica albuginea 2. tunica vaginalis 3. mediastinum testis 4. septa 5. testicular lobules. II. Testis. B. Parenchyma (22.1) 1. Seminiferous tubules 2. Straight tubules 3. Rete testis 4. Ductuli efferentes.

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22 male reproductive system

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    1. 22 Male Reproductive System I. Overview II. Testes III. Epididymis IV. Ductus (Vas) Deferens V. Accessory Glands VI. Penis

    3. II. Testis A. Stroma (22.1) 1. tunica albuginea 2. tunica vaginalis 3. mediastinum testis 4. septa 5. testicular lobules

    4. II. Testis B. Parenchyma (22.1) 1. Seminiferous tubules 2. Straight tubules 3. Rete testis 4. Ductuli efferentes

    5. II. Testis C. Seminiferous tubules (22.2) 1. ~ 250 m / testis 2. stratified (germinal) epithelium a. spermatogenic cells b. Sertoli cells 3. basal lamina with myoid cells 4. ~ 150-250 mm diam. 5. CT layer

    6. II. Testis D. Spermatogenesis (22.4,22.5) 1. spermatogonia a. basal lamina b. mitotic 2. 1o spermatocyte a. large cells b. meiosis

    7. II. Testis D. Spermatogenesis (22.4,22.6) 3. 2o spermatocytes a. from 1st meiotic division b. short lived 4. spermatids a. from 2nd meiotic division b. 4 from each daughter cell

    8. II. Testis E. Spermatogenesis vs. spermiogenesis (22.7) 1. spermatogonia to spermatozoan: 64 days 2. spermatogenesis occurs in waves along seminiferous tubules 3. Each cross section of tubule will show a different stage of development

    9. II. Testis F. Spermiogenesis 1. spermatid to mature spermatozoon (22.9)

    10. II. Testis F. Spermiogenesis 2. Golgi Phase (22.9) a. prominent Golgi complex b. acrosomal vesicle c. centioles opposite acrosome

    11. II.Testis F. Spermiogenesis 3. Acrosomal Phase (22.9) a. acrosome next to nucleus b. anterior pole towards basal lamina c. nucleus elongated and condensed d. 1 centriole forms flagellum e. mitochondria around base of flagellum

    12. II. Testis EM of Acrosomal Phase of spermiogenesis 22-10

    13. II.Testis F. Spermiogenesis 4. Maturation Phase (22.9,22.11) a. residual body shed b. spermatozoan released into lumen

    14. II. Testis G. Sertoli cells 1. extend from basal lamina to lumen (22.4) 2. lateral surface intedigitates with spermatogenic cells 3. prominent nucleolus 4. rat - Sertoli cells only at BM (?)

    15. II. Testis G. Sertoli cells 3. blood-testis barrier (22.12) a. tight and gap junctions b. basal compartment c. adluminal compartment

    16. II. Testis G. Sertoli cells 4. functions a. support spermatogenesis (22.12) 1) physical support 2) nutritional support

    17. II. Testis G. Sertoli cells 4. functions b. phagocytosis (22.12) 1) residual bodies

    18. II. Testis G. Sertoli cells 22.12 4. functions c. secretion 1) vehicle for sperm 2) androgen binding protein 3) converts testosterone to estradiol 4) inhibin: decr. FSH in pituitary

    19. II. Testis H. Interstitial (Leydig) Cells 1. round cell (22.4,22.3) 2. central nucleus 3. acidophilic cytoplasm 4. lipid droplets 5. secretes testosterone

    20. II. Testis H. Interstitial Cells 22-14

    21. III. Epididymis A. Pseudostratified columnar epithelium (22.1,22.15) 1. stereocilia 2. uptake & digestion of residual bodies B. Smooth muscle C. Storage and Maturation of sperm

    22. IV. Ductus (vas) deferens A. Pseudostratified columnar epithelium (22.1,22.16) 1. stereocilia B. Lamina propria with elastic fibers

    23. IV. Ductus deferens C. Muscularis (22.16) 1. inner longitudinal 2. mddle circular 3. outer longitudinal

    24. IV. Ductus deferens D. Spermatic cord 1. ductus deferens 2. testicular artery 3. pampiniform plexus a. venous network to remove heat from artery 4. nerves

    25. V. Accessory Glands A. Seminal vesicles 1. two convoluted tubes (22.1,22.17) 2. folded mucosa 3. pseudostratified columnar epithelium 4. lamina propria with elastic fibers 5. smooth muscle fibers

    26. V. Accessory Glands A. Seminal vesicles 22-17 6. secretion a. spermatozoa activating substances b. CHO nutrition for spermatozoa

    27. V. Accessory Glands B. Prostate gland 1. 30-50 branched tubuloalveolar glands (22.18,22.19) 2. open into prostatic urethra

    28. V. Accessory Glands B. Prostate gland(22.20) 3. epithelium a. pseudostratified columnar b. simple columnar c. simple cuboidal 4. stroma a. fibroelastic CT b. smooth muscle fibers 5. prostatic concretions (corpora amylacea) - eosinophilic

    29. VI. Penis A. Erectile tissue (22.21) 1. two corpora cavernosa 2. corpus spongiosum or corpus cavernosum of the urethra

    30. VI. Penis A. Erectile tissue (22.17) 3. tunica albuginea 4. venous spaces 5. trabeculae a. CT b. smooth muscle

    31. VI. Penis B. Erection 1. parasympathetic input 2. inhibition of sympathetic vasoconstriction 3. vasodilation of penile vessels 4. engorgment of erectile tissue C. Ejaculation 1. sympathetic peristaltic contraction of tubes and ducts 2. vasoconstriction of blood vessels 3. flaccid penis

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