Yasmin Birth Control Tablets (Drospirenone and Ethinyl Estradiol Pills)

1. Yasmin Birth Control Tablets (Drospirenone and Ethinyl Estradiol Pills) © All Contraceptives

2. Yasmin Birth Control Tablets (Drospirenone and Ethinyl Estradiol Pills) Yasmin Birth Control Tablets (Drospirenone and Ethinyl Estradiol Pills) provides an oral contraceptive regimen consisting of 21 active film coated tablets each containing 3 mg of Drospirenone and 0.03 mg of Ethinyl Estradiol. Yasmin is used to prevent pregnancy. Yasmin is also of some benefit in androgen-related acne, skin conditions or greasy hair. Women taking Yasmin may also experience the following benefits:improvement in symptoms like bloating, swelling or weight gain related to fluid retention, more regular and lighter periods and a decrease in period pain. Some conditions such as pelvic inflammatory disease, ovarian cysts, ectopic pregnancy, fibrocystic breast changes and cancer of the uterus (womb) and ovaries may be less common in women taking the Pill. © All Contraceptives

3. Yasmin Birth Control Tablets (Drospirenone and Ethinyl Estradiol Pills) Active Ingredient The active pharmaceutical ingredients contained in Yasmin tablets are Drospirenone and Ethinyl Estradiol. Each film coated yellow tablet contains 3 mg Drospirenone (DRSP) and 0.03 mg Ethinyl Estradiol (EE). © All Contraceptives

4. Yasmin Birth Control Tablets (Drospirenone and Ethinyl Estradiol Pills) Chemical Structure - Drospirenone © All Contraceptives

5. Yasmin Birth Control Tablets (Drospirenone and Ethinyl Estradiol Pills) Chemical Structure - Ethinyl Estradiol © All Contraceptives

6. Yasmin Birth Control Tablets (Drospirenone and Ethinyl Estradiol Pills) Yasmin Tablets Yasmin Tablets are marketed by Bayer Zydus Pharma Private Limited, India and manufactured by Bayer AG, Berlin, Germany. They are available in a box with 21 film coated yellow tablets, each containing 3 mg Drospirenone (DRSP) and 0.03 mg Ethinyl Estradiol (EE). (Website: https://www.bayer.com/en/ https://www.bayer.com/en/ ) URL: URL: https://www.allcontraceptives.com/yasmin-birth-control-pills.html https://www.allcontraceptives.com/yasmin-birth-control-pills.html © All Contraceptives

7. Yasmin Birth Control Tablets (Drospirenone and Ethinyl Estradiol Pills) Uses of Yasmin Tablets Drospirenone and Ethinyl Estradiol combination (Yasmin tablets) is used to prevent pregnancy. It is a birth control pill that contains two types of hormones, Drospirenone and Ethinyl Estradiol, and when taken properly, prevents pregnancy. This medication works by preventing ovulation (the release of an egg from an ovary) and by causing changes in the mucus of the cervix (that makes it difficult for sperm to penetrate into the uterus) and in the endometrium (that make it difficult for an egg to implant). This medicine is also used to treat premenstrual dysphoric disorder (PMDD) in women at least 16 years of age. URL: URL: https://www.allcontraceptives.com/yasmin-birth-control-pills.html https://www.allcontraceptives.com/yasmin-birth-control-pills.html © All Contraceptives

8. Yasmin Birth Control Tablets (Drospirenone and Ethinyl Estradiol Pills) Uses of Yasmin Tablets PMDD is a severe form of premenstrual syndrome (PMS). Patients with PMDD may have severe emotional and physical symptoms 10 to 14 days before their menstrual flow starts. Drospirenone and Ethinyl Estradiol tablets are also used to treat moderate acne for women over 16 years of age who also want birth control and have started menstruating. URL: URL: https://www.allcontraceptives.com/yasmin-birth-control-pills.html https://www.allcontraceptives.com/yasmin-birth-control-pills.html © All Contraceptives

9. Yasmin Birth Control Tablets (Drospirenone and Ethinyl Estradiol Pills) Recommended Dosage The dosage of Yasmin Tablets Yasmin Tablets (Drospirenone and Ethinyl Estradiol Tablets) is given below: Take one tablet by mouth at the same time every day. The failure rate may increase when pills are missed or taken incorrectly. To achieve maximum contraceptive effectiveness, Yasmin must be taken as directed, in the order directed on the blister pack. Single missed pills should be taken as soon as remembered. How to Start Yasmin: How to Start Yasmin: The patient has to begin taking Yasmin either on the first day of her menstrual period (Day 1 Start) or on the first Sunday after the onset of her menstrual period (Sunday Start). URL: URL: https://www.allcontraceptives.com/yasmin-birth-control-pills.html https://www.allcontraceptives.com/yasmin-birth-control-pills.html © All Contraceptives

10. Yasmin Birth Control Tablets (Drospirenone and Ethinyl Estradiol Pills) Recommended Dosage Day 1 Start: During the first cycle of Yasmin use, instruct the patient to take one yellow Yasmin daily, beginning on Day 1 of her menstrual cycle. (The first day of menstruation is Day 1.) She should take one yellow Yasmin daily for 21 consecutive days, followed by 7 tablet free days. Yasmin should be taken in the order directed on the package at the same time each day, preferably after the evening meal or at bedtime with some liquid, as needed. Yasmin can be taken without regard to meals. If Yasmin is first taken later than the first day of the menstrual cycle, Yasmin should not be considered effective as a contraceptive until after the first 7 consecutive days of product administration. Instruct the patient to use a non-hormonal contraceptive as back-up during the first 7 days. The possibility of ovulation and conception prior to initiation of medication should be considered. URL: URL: https://www.allcontraceptives.com/yasmin-birth-control-pills.html https://www.allcontraceptives.com/yasmin-birth-control-pills.html © All Contraceptives

11. Yasmin Birth Control Tablets (Drospirenone and Ethinyl Estradiol Pills) Recommended Dosage Sunday Start: During the first cycle of Yasmin use, instruct the patient to take one yellow Yasmin daily, beginning on the first Sunday after the onset of her menstrual period. She should take one yellow Yasmin daily for 21 consecutive days, followed by 7 tablet free days. Yasmin should be taken in the order directed on the package at the same time each day, preferably after the evening meal or at bedtime with some liquid, as needed. Yasmin can be taken without regard to meals. Yasmin should not be considered effective as a contraceptive until after the first 7 consecutive days of product administration. Instruct the patient to use a non-hormonal contraceptive as back-up during the first 7 days. The possibility of ovulation and conception prior to initiation of medication should be considered. The patient should begin her next and all subsequent 21-day regimens of Yasmin on the same day of the week that she began her first regimen, following the same schedule. She should begin taking her yellow tablets on the next day after ingestion of the last white tablet, regardless of whether or not a menstrual period has occurred or is still in progress. © All Contraceptives

12. Yasmin Birth Control Tablets (Drospirenone and Ethinyl Estradiol Pills) Missed Dose Instructions If you miss 1 yellow pill of your pack: 1. Take it as soon as you remember. Take the next pill at your regular time. This means you may take two pills in one day. 2. You do not need to use a back-up birth control method if you have sex. If you miss 2 yellow pills in a row in Week 1 or Week 2 of your pack: 1. Take two pills on the day you remember and two pills the next day. 2. Then take one pill a day until you finish the pack. 3. You could become pregnant if you have sex in the 7 days after you restart your pills. You must use another birth control method (such as a condom and spermicide) as a back-up for those 7 days. URL: URL: https://www.allcontraceptives.com/yasmin-birth-control-pills.html https://www.allcontraceptives.com/yasmin-birth-control-pills.html © All Contraceptives

13. Yasmin Birth Control Tablets (Drospirenone and Ethinyl Estradiol Pills) Missed Dose Instructions If you miss 2 yellow pills in a row in Week 3 or Week 4 of your pack: 1. If you are a Day 1 Starter: Throw out the rest of the pill pack and start a new pack that same day. 2. If you are a Sunday Starter: Keep taking one pill every day until Sunday. On Sunday, throw out the rest of the pack and start a new pack of pills that same day. 3. You could become pregnant if you have sex in the 7 days after you restart your pills. You must use another birth control method (such as a condom and spermicide) as a back-up for those 7 days. 4. You may not have your period this month but this is expected. However, if you miss your period two months in a row, call your healthcare provider because you might be pregnant. URL: URL: https://www.allcontraceptives.com/yasmin-birth-control-pills.html https://www.allcontraceptives.com/yasmin-birth-control-pills.html © All Contraceptives

14. Yasmin Birth Control Tablets (Drospirenone and Ethinyl Estradiol Pills) Missed Dose Instructions If you miss 3 or more yellow pills in a row during any week: 1. If you are a Day 1 Starter:Throw out the rest of the pill pack and start a new pack that same day. 2. If you are a Sunday Starter:Keep taking 1 pill every day until Sunday. On Sunday, throw out the rest of the pack and start a new pack of pills that same day. 3. You could become pregnant if you have sex in the 7 days after you restart your pills. You must use another birth control method (such as condoms and spermicides) as a back-up for those 7 days. 4. You may not have your period this month but this is expected. However, if you miss your period two months in a row, call your healthcare provider because you might be pregnant. URL: URL: https://www.allcontraceptives.com/yasmin-birth-control-pills.html https://www.allcontraceptives.com/yasmin-birth-control-pills.html © All Contraceptives

15. Yasmin Birth Control Tablets (Drospirenone and Ethinyl Estradiol Pills) Contraindications Yasmin Tablets are contraindicated in patients with a hypersensitivity to Drospirenone, Ethinyl Estradiol or any other component of this medication. They are also contraindicated in cases of: Renal impairment Adrenal insufficiency A high risk of arterial or venous thrombotic diseases. Examples include women who are known to: Smoke, if over age 35, have deep vein thrombosis or pulmonary embolism, now or in the past, have cerebrovascular disease, have coronary artery disease, have thrombogenic valvular or thrombogenic rhythm diseases of the heart (for example, subacute bacterial endocarditis with valvular disease, or atrial fibrillation) URL: URL: https://www.allcontraceptives.com/yasmin-birth-control-pills.html https://www.allcontraceptives.com/yasmin-birth-control-pills.html © All Contraceptives

16. Yasmin Birth Control Tablets (Drospirenone and Ethinyl Estradiol Pills) Contraindications They are also contraindicated in cases of: They are also contraindicated in cases of: Have inherited or acquired hypercoagulopathies Have uncontrolled hypertension Have diabetes mellitus with vascular disease Have headaches with focal neurological symptoms or have migraine headaches with or without aura if over age 35 Undiagnosed abnormal uterine bleeding Breast cancer or other estrogen- or progestin-sensitive cancer, now or in the past Liver tumor (benign or malignant) or liver disease Pregnancy or suspected pregnancy because there is no reason to use Combine Oral Contraceptives during pregnancy URL: URL: https://www.allcontraceptives.com/yasmin-birth-control-pills.html https://www.allcontraceptives.com/yasmin-birth-control-pills.html © All Contraceptives

17. Yasmin Birth Control Tablets (Drospirenone and Ethinyl Estradiol Pills) Storage Instructions Yasmin Tablets (Drospirenone and Ethinyl Estradiol Tablets) have to be stored at controlled room temperature i.e. from 20°C to 25°C (68°F to 77°F) with excursions permitted between 15° to 30°C (59° to 86°F). Keep this as well as all other medicines away from children and pets. URL: URL: https://www.allcontraceptives.com/yasmin-birth-control-pills.html https://www.allcontraceptives.com/yasmin-birth-control-pills.html © All Contraceptives

18. Yasmin Birth Control Tablets (Drospirenone and Ethinyl Estradiol Pills) Warnings Vascular risks: Stop Yasmin if a thrombotic event occurs. Stop at least 4 weeks before and through 2 weeks after major surgery. Start no earlier than 4 weeks after delivery, in women who are not breastfeeding. Hyperkalemia: DRSP has antimineralocorticoid activity. Do not use in patients predisposed to hyperkalemia. Check serum potassium concentration during the first treatment cycle in women on long-term treatment with medications that may increase serum potassium concentration. Liver disease: Discontinue Yasmin if jaundice occurs. High blood pressure: Do not prescribe Yasmin for women with uncontrolled hypertension or hypertension with vascular disease. URL: URL: https://www.allcontraceptives.com/yasmin-birth-control-pills.html https://www.allcontraceptives.com/yasmin-birth-control-pills.html © All Contraceptives

19. Yasmin Birth Control Tablets (Drospirenone and Ethinyl Estradiol Pills) Warnings Carbohydrate and lipid metabolic effects: Monitor prediabetic and diabetic women taking Yasmin. Consider an alternate contraceptive method for women with uncontrolled dyslipidemia. Headache: Evaluate significant change in headaches and discontinue Yasmin if indicated. Uterine bleeding: Evaluate irregular bleeding or amenorrhea. URL: URL: https://www.allcontraceptives.com/yasmin-birth-control-pills.html https://www.allcontraceptives.com/yasmin-birth-control-pills.html © All Contraceptives

20. Yasmin Birth Control Tablets (Drospirenone and Ethinyl Estradiol Pills) Side Effects The most frequent Yasmin tablets side effects with an incidence rate of 2% and greater are premenstrual syndrome (13.2%), headache /migraine (10.7%), breast pain/tenderness/discomfort (8.3%), nausea/vomiting (4.5%), abdominal pain/tenderness/discomfort (2.3%), mood changes (2.3%). URL: URL: https://www.allcontraceptives.com/yasmin-birth-control-pills.html https://www.allcontraceptives.com/yasmin-birth-control-pills.html © All Contraceptives

21. Yasmin Birth Control Tablets (Drospirenone and Ethinyl Estradiol Pills) Overdose There have been no reports of serious ill effects from overdose, including ingestion by children. Overdosage may cause withdrawal bleeding in females and nausea. DRSP is a spironolactone analogue which has antimineralocorticoid properties. Serum concentration of potassium and sodium, and evidence of metabolic acidosis, should be monitored in cases of overdose. URL: URL: https://www.allcontraceptives.com/yasmin-birth-control-pills.html https://www.allcontraceptives.com/yasmin-birth-control-pills.html © All Contraceptives

22. Yasmin Birth Control Tablets (Drospirenone and Ethinyl Estradiol Pills) Yasmin Tablets During Pregnancy Yasmin Tablets (Drospirenone and Ethinyl Estradiol Tablets) has been classified by the US FDA as Pregnancy Category X. There is little or no increased risk of birth defects in women who inadvertently use COCs during early pregnancy. Epidemiologic studies and meta-analyses have not found an increased risk of genital or non-genital birth defects (including cardiac anomalies and limb-reduction defects) following exposure to low dose COCs prior to conception or during early pregnancy. The administration of COCs to induce withdrawal bleeding should not be used as a test for pregnancy. COCs should not be used during pregnancy to treat threatened or habitual abortion. URL: URL: https://www.allcontraceptives.com/yasmin-birth-control-pills.html https://www.allcontraceptives.com/yasmin-birth-control-pills.html © All Contraceptives

23. Yasmin Birth Control Tablets (Drospirenone and Ethinyl Estradiol Pills) Yasmin Tablets During Nursing When possible, the nursing mother should use other forms of contraception until she has weaned her child. Estrogen-containing COCs can reduce milk production in breastfeeding mothers. This is less likely to occur once breastfeeding is well-established; however, it can occur at any time in some women. Small amounts of oral contraceptive steroids and/or metabolites are present in breast milk. URL: URL: https://www.allcontraceptives.com/yasmin-birth-control-pills.html https://www.allcontraceptives.com/yasmin-birth-control-pills.html © All Contraceptives

24. Yasmin Birth Control Tablets (Drospirenone and Ethinyl Estradiol Pills) Yasmin Tablets Yasmin Tablets (Drospirenone and Ethinyl Estradiol Tablets) marketed by Bayer Zydus Pharma Private Limited, India and manufactured by Bayer AG, Berlin, Germany. URL: URL: https://www.allcontraceptives.com/yasmin-birth-control-pills.html https://www.allcontraceptives.com/yasmin-birth-control-pills.html © All Contraceptives