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Håndtering af gravide med cervikal dysplasi .

Håndtering af gravide med cervikal dysplasi. PICO. P: Graviditet, cervical dysplasi I: Konisatio C: Konservativ beh. O: Cervix cancer. Litteratur søgning. Pubmed Pregnancy AND cervical dysplasi 780 AND conization 128 ref.1 review

angelica-jimenez
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Håndtering af gravide med cervikal dysplasi .

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  1. Håndtering af gravide med cervikaldysplasi.

  2. PICO • P: Graviditet, cervical dysplasi • I: Konisatio • C: Konservativ beh. • O: Cervix cancer

  3. Litteratur søgning. Pubmed Pregnancy AND cervicaldysplasi 780 AND conization 128 ref.1 review ref.2 (part 1 and 2) AND cochrane 1 ref.3 Pubmed Preview/Index (ACTA): Pregnancy AND cervicaldysplasia AND conization 11 ref.4

  4. Ref. 1

  5. Ref.2 2008

  6. Ref.3

  7. Ref.4

  8. Udvælgelses kriterier • Ny forskning – siden 2000 • Review Ref.2 • Meta-analyse. Cochrane review Ref.3 • Repræsentativt (ACTA – danske kohorte 305) Ref.4 • Repræsentativt (ACTA - italiensk prospektivt case-kontrol 80/78) Ref.1 Udtømmende svar på spørgsmål:JA

  9. Faktuelle statements • Natur historie: gravide har mindre progressions risiko smlg. med ikke gravide. • Kolposkopi og biopsi er sikker kontrol metode ved gravide. (som hos ikke gravide) • Flow-chart: Ref.2

  10. Evidens grad • Ref. 1: Italiensk prospektivcase-kontrol C (III) • Ref. 2: Amerikansk review A (Ia) • Ref. 3: Cochrane metaanalyse A (Ia) • Ref. 4: Dansk retrospektiv kohorte B (IIb)

  11. Kliniske anbefalinger • Gravide med cervikal dysplasi kan beh. konservativt med kolposkopi og biopsi hver 3. md. (Flow-chart)

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