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Endocrine System

This lab will cover the anatomy and histology of the thyroid, adrenal, and hypophysis glands, including their structures, cell types, and functions. Quiz 3 will also be conducted. Presented by Jun Zhou, School of Medicine, Zhejiang University.

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Endocrine System

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  1. Endocrine System • Thyroid gland (No.35) • Adrenal gland (No.36) • Hypophysis (No.37) • Next Lab: Quiz3 • (Dig glands.Res.Uri.Endo.System) Jun Zhou School of Medicine, Zhejiang University

  2. Thyroid gland isthmus lobe Overview • Capsule • Parenchyma • follicles with pink colloid • interfollicle stroma

  3. Follicle 1)Follicular cells Simble cuboidal epi Columnar (stimulated) Squamous (inactive) 2)Parafollicular cells 3)Colloid • Interfollicle stroma

  4. colloid Follicular cell: Simple cuboidal epithelium

  5. P P Parafollicular cells

  6. Parafollicular cells, silver-stained

  7. Adrenal gland • Capsule • Cortex • Medulla

  8. Zona glomerulosa Zona fasiculata Cortex Zona reticularis • zona glomerulosa • zona fasiculata • zona reticularis

  9. capsule Zona glomerulosa Zona fasiculata Zona reticularis

  10. Zona glomerulosa Zona glomerulosa • Small cells in clusters • A few lipid droplets

  11. Zona fasciculata Zona fasciculata • Occupies large portion of the cortex • Arranged in cords • A lot of lipid droplets

  12. Zona reticularis • Zona reticularis • Smaller, deep red-stained cytoplasm • Forming anatomizing network

  13. Medulla Medullary vein Medulla • Chromaffin cells: polyhedral, with chromaffin granules • Medullary vein

  14. Chromaffin cells

  15. Medulla: Sympathetic ganglionic cells neuron

  16. Hypophysis (Pituitary gland) adenohypophysis • Pars distalis • Pars intermedia • Pars tuberalis neurohypophysis • Pars nervosa • stalk

  17. Infundibular stalk Pars distalis Pars nervosa Pars intermedia Hypophysis

  18. Pars distalis Pars nervosa

  19. Pars distalis • Acidophilic cells • Basophilic cells:peripherally located • Chromophobe cells:most numerous

  20. Pars Distalis Acidophil Basophil Chromophobes

  21. Pars distalis

  22. Pars intermedia • Follicles • Basophilic cells

  23. Pars nervosa:unmyelinated nerve fiber Herring body

  24. Pars distalis Pars intermedia Pars nervosa

  25. lipofuscin

  26. The end!

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