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Preformulated Antacid Suspensions

Preformulated Antacid Suspensions. Advantages of CoBlends. What is a CoBlend ?. A pumpable and homogeneous suspension containing. Sorbitol Antacid Actives Aluminum Hydroxide Magnesium Hydroxide Ready for Suspension

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Preformulated Antacid Suspensions

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  1. PreformulatedAntacid Suspensions Advantages of CoBlends

  2. Whatis a CoBlend ? A pumpableand homogeneous suspension containing • Sorbitol • Antacid Actives • Aluminum Hydroxide • Magnesium Hydroxide • Ready for Suspension • A simpler, better and less expensive way to make Antacid Suspensions • A customized formula • An excellent taste and mouthfeel

  3. Typical CoBlends

  4. Standard AMS CoBlends • Single strength formulations require suspending agents, thickeners • Double strength formulations may or may not require suspending agents or thickeners-depends on the desired final formulation viscosity • Highly consistent assays • All CoBlends contain propyl paraben preservatives • Custom Combination preservatives: • Methyl and Propyl • Butyl and Propyl

  5. Particle Size

  6. Higher yields Less QC testing Lower labor and capital costs Reduced inventory: one ingredient instead of several Reduces manufacturing steps Requires only final blending step: frees up capacity Cost Reduction and Key Features

  7. Advantages: CoBlend System vs Classical Formulation QC CoBlend=1 Raw Material QC Single Active ingredients =2 Raw Materials | Pump CoBlend suspension | | Add water Final Blend with ingredients to produce desired antacid concentration | Weight and dump each single active ingredient | | QC for release Homogenization | | Bottling Equipment Add Suspending Agent | | Antacid suspension Blend to achieve proper viscosity | QC for Assay and viscosity | Final Blend with ingredients to produce desired antacid concentration | Bottling equipment | Antacid Suspension | QC for release

  8. BenefitsWithCoBlends • Pumpableproduct: improvesproduct handling operation • Improve taste and mouthfeel • Higherreactivity (AcidNeutralizationCapacity) • Lowercost of manufacturing • Elegant and consistent suspension • Simplermanufacturingprocess • Customized formulation

  9. Plastic Drums at 205 kg Bulk Tanker Truck (for large quantities when possible) Totes 1,000 liters (Preferred mode for international shipments) 1,000 liter export containers for non-hazardous liquids Valve-in-Place (VIP) Tote Packaging has Superior strength and durability Higher stacking ( up to 4 high) Easy disposability-recyclable, biodegradable, and waste-to-energy efficient Minimizes product handling-1 tote equals about 6 drums High yield of product SpaceKraftTotes www. spacekraft.com CoBlendPackaging Options

  10. Applications • Success stories from Antacid university • Video of production of classic vsCoBlend way • Suspension decision guide • CoBlenddevelopment form

  11. CoBlendPreformulated Suspensions Fast Acting Relief for the Manufacturing Process

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