1 / 7

Osteogenesis Imperfecta

Osteogenesis Imperfecta. Miya Kusumoto IB Biology, Pd 4/5. Facts. Osteogenesis Imperfecta (OI) is a genetic disorder in which bones break easily. There are 8 recognized types, Type I being the mildest and Type II being the most severe.

bisa
Télécharger la présentation

Osteogenesis Imperfecta

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. OsteogenesisImperfecta Miya Kusumoto IB Biology, Pd 4/5

  2. Facts • OsteogenesisImperfecta (OI) is a genetic disorder in which bones break easily. • There are 8 recognized types, Type I being the mildest and Type II being the most severe. • 85-90% of OI cases are caused by a dominant genetic defect • There is not an actual cure for OI, but there are treatments that can control or prevent the symptoms

  3. Causes and Treatment • OI is has an autosomal dominant inheritance pattern, meaning that a person will still have OI even though only 1 faulty gene is being passed. • OI is caused by a mutation on a gene that affects the body’s production level of collagen found in bones and tissues • Because there is no specific cure for OI, doctors focus on finding ways to minimize fractures, maximize mobility, and improve general health. • So, some of the treatments include swimming, physical therapy, casts, splints, medications, and orthopedic surgery

  4. Symptoms Type I OI Type II OI • Bones Fracture easily • Weak Muscles and loose joints • Purple, Blue, or Grey tinted sclera (whites of the eye) • Triangular Face • Brittle Teeth • Hard to live after birth because of respiratory problems • Severe and numerous fractures and bone deformities • Small build with underdeveloped lungs • Tinted Sclera • Improperly formed collagen

  5. More Info • It is estimated that 20,000-50,000 people in the U.S. have OI • Affects about 6-7 people per 100,000 worldwide • Types I and IV are the most common

  6. Societal Issues • There aren’t any major societal issues, in many of the mild cases, it is barely recognizable • OI cases appear to be similar worldwide, but there is an increased rate observed in 2 major tribal groups in Zimbabwe.

  7. Bibiliography • http://www.oif.org/site/PageServer • http://www.nlm.nih.gov/medlineplus/osteogenesisimperfecta.html • http://emedicine.medscape.com/article/947588-overview • http://my.clevelandclinic.org/disorders/osteogenesis_imperfecta/hic_osteogenesis_imperfecta.aspx

More Related