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DNA Replication

DNA Replication. The structure of DNA consists of two polynucleotide strands wrapped around each other in a double helix. 1 chocolate coat, Blind (PRA). Figure 10.3C. Twist. Each base pairs with a complementary partner A pairs with T G pairs with C.

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DNA Replication

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  1. DNA Replication

  2. The structure of DNA consists of two polynucleotide strands wrapped around each other in a double helix 1 chocolate coat, Blind (PRA) Figure 10.3C Twist

  3. Each base pairs with a complementary partner • A pairs with T • G pairs with C • Hydrogen bonds between bases hold the strands together

  4. Three representations of DNA Hydrogen bond Ribbon model Partial chemical structure Computer model Figure 10.3D

  5. DNA REPLICATION 10.4 DNA replication depends on specific base pairing • In DNA replication, the strands separate • Enzymes assemble the new strands • With each strand serving as a template A A Nucleotides Parental moleculeof DNA Both parental strands serveas templates Two identical daughtermolecules of DNA Figure 10.4A

  6. Untwisting and replication of DNA Figure 10.4B

  7. 10.5 DNA replication: A closer look • DNA replication begins at specific sites Parental strand Origin of replication Daughter strand Bubble Two daughter DNA molecules Figure 10.5A

  8. 5 end 3 end P • Each strand of the double helix is oriented in the opposite direction P P P P P P P 3 end 5 end Figure 10.5B

  9. 3 DNA polymerasemolecule 5 5 end Daughter strandsynthesizedcontinuously Parental DNA 5 3 Daughter strandsynthesizedin pieces • How DNA daughter strands are synthesized 3 P 5 • The daughter strands are identical to the parent molecule 5 P 3 DNA ligase Overall direction of replication Figure 10.5C

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