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Fluconazole By

Fluconazole By. Latonya Miles 2 nd period Mr. Davis Botany Class. Classification. Availability. Pharmacokinetics. Fluconazole is almost completely absorbed within two hours.

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Fluconazole By

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  1. FluconazoleBy Latonya Miles 2nd period Mr. Davis Botany Class

  2. Classification

  3. Availability

  4. Pharmacokinetics • Fluconazole is almost completely absorbed within two hours. • The elimination half-life of fluconazole follows zero order kinetics and only 10% of elimination is due to metabolism. • Patients with impaired renal function will be at risk of overdose as well as patients taking drugs such as warfarin.

  5. Action/Therapeutic Effect

  6. Uses • Fluvonazole is an azole antifungal medication used to prevent and treat a variety of fungal and yeast infections.

  7. Administration • Single dose • The recommended dosage is 150 mg as a single oral dose. • Fluconazole may be administered either orally or by intravenous infusion. • Fluconazole injection has been used safely for up to 14 days of intravenous therapy.

  8. Indication • Fluconazole is indicated for the treatment and prophylaxis of fungal infections where other antifungal have failed or are not tolerated including: • Candidiasis- caused by susceptible strains of Candida • Tinea corporis • The drug may make you dizzy • Use caution engaging in activities requiring alertness such as driving or using machinery. • This medication should be used only when clearly needed during pregnancy.

  9. Precautions • Before you take Fluconazole you have to tell your doctor if you are allergic to it. • Do not use if the solution is cloudy or precipitated or if seal is not intact. • Parental drug products should be inspected visually for particulate matter and discoloration prior to administration whenever solution and container permit.

  10. Interactions(what causes increase damage when mixed with it) • Fluconazole is an inhibitor of the human cytochrome P450 system, particularly the isozymes CYP2C9 and CYP3A4. • In theory, therefore, fluconazole decreases the metabolism and increases the concentration of any drug metabolised by these enzymes. • Additionally, its potential effect on QT interval increases the risk of cardiac arrhythmia if used concurrently with other drugs that prolong the QT interval.

  11. Side of Effects

  12. Adverse Reactions/Toxic Effects

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