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Transcriptional Specificity of Dysfusion

Transcriptional Specificity of Dysfusion. Dys Forms a Heterodimer with Tgo In Vivo. Ectopic Dys Expression cause ectopic Tgo nuclear Localization. Dys::Tgo Activates TCGTG, GCGTG and ACGTG in S2 Cell Culture. Nxf::Arnt and Nxf::Tgo Activates TCGTG,GCGTG and ACGTG. Trh:Tgo Activates ACGTG.

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Transcriptional Specificity of Dysfusion

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  1. Transcriptional Specificity of Dysfusion

  2. Dys Forms a Heterodimer with Tgo In Vivo

  3. Ectopic Dys Expression cause ectopic Tgo nuclear Localization

  4. Dys::Tgo Activates TCGTG, GCGTG and ACGTG in S2 Cell Culture

  5. Nxf::Arnt and Nxf::Tgo Activates TCGTG,GCGTG and ACGTG

  6. Trh:Tgo Activates ACGTG

  7. Sim::Tgo Activates ACGTG

  8. Basic region alignment of selected bHLH-PAS proteins NC/GTG

  9. Identification of Dys taget gene CG13196 Enhancer

  10. Fusion cell expression of CG13196 requires TCGTG sequences

  11. Misexpression of dys results in ectopic expression of Dys target gene CG13196 in multiple cell types

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