1 / 25

Case 1 : Intraoperative FNA and biopsy of the pancreas

Case 1 : Intraoperative FNA and biopsy of the pancreas. Maryam Mehdizadeh MD,MIAC. A 56-year-old woman with nausea,abdominal pain and jaundice since four weeks ago and mass lesion in head of pancreas in C T scan. Ductal adenocarcinoma of the pancreas.

clare
Télécharger la présentation

Case 1 : Intraoperative FNA and biopsy of the pancreas

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Case 1 :Intraoperative FNA and biopsy of the pancreas Maryam Mehdizadeh MD,MIAC

  2. A 56-year-old woman with nausea,abdominal pain and jaundice since four weeks ago and mass lesion in head of pancreas in C T scan

  3. Ductaladenocarcinoma of the pancreas Well differentiated) )

  4. Well differentiated ductal adenocarcinoma 1. Malignant cells are arranged in large folded sheets and three-dimensional groups or demonstrate and exag- gerated honeycomb pattern. periph-2. Abnormal groups may be cohesive and lack eral feathering . 3.The nuclei are crowded , lose their roundness and sm- oothness and become angulated and pyramidal or carrot-shaped with focal notches and grooves . 4.Anisocytosis , nuclear enlargement , irregular chromatin clearing . 5.Mitosis and necrosis are infrequent.

  5. Moderately and poorly differentiated adenocarcinoma 1.Malignant cells are arranged in crowded, three dimensional groups or groups with an exag- gerated honeycomb pattern. 2. Single cells with significant atypia . .The nuclei are more frequently notched or 3 deeply grooved and convoluted. 4.The nuclei are typically more hyperchromatic. 5. Mitosis are more common. 6.The smear pattern is more often necrotic .

  6. Undifferentiated(anaplastic)adenocarcinoma Very cellular smear Bizarre spindle shaped cells associated with num- erous single sarcomatoid appearing malignant cells and multinucleated giant cells Cytophagocytosis and tumor necrosis

  7. Biopsy of the pancreas

More Related