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Update: Bio-economy Strategy

Update: Bio-economy Strategy. Presentation to the Portfolio Committee 27 May 2015. Outline. The Bio-economy Strategy Definition; Systems approach; Metrics; Opportunity; Challenges; & Governance Actions and activities: Agriculture Health Innovation Industry & Environment

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Update: Bio-economy Strategy

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  1. Update: Bio-economy Strategy Presentation to the Portfolio Committee 27 May 2015

  2. Outline • The Bio-economy Strategy • Definition; Systems approach; Metrics; • Opportunity; Challenges; & Governance • Actions and activities: • Agriculture • Health Innovation • Industry & Environment • IKS-based Technology Innovation

  3. Defining the Bio-economy Refers to activities that make use of bio-innovations, based on biological sources, materials and processes to generate sustainable economic social and environmental development. In consultation with relevant stakeholders, the DST “has identified 3 key economic sectors – agriculture, health and industry – as being the most in need of, and likely to benefit from key levers to drive the implementation of the [strategy]” Agriculture Health Industry & Environment

  4. So what is new in the Bio-economy strategy? Opportunistic • Coordinated, specific • Focused Value Chain • (c) System enablers

  5. Private sector not-for-profit Aeras, Aurum, MMV, EDCTP MBI The Bio-related NSI Government Departments CSIR DRDLR DST Universities DEA Funding Bodies DoH NRF DTI DAFF Provincial Research Institutes MRC ARC Science Councils R,D & I TIA ICGEB IDC -VCs Bio-economy Platforms & service providers PPPs eg Biovac PUBLIC Private sector BiosafetySAPrograrmme PUB Prog Pharmaceutical; Agricultural; Industrial Communities; NGO’s; interface with science and business Gates Rockerfeller, Foundations SAPPI/Mondi; Winter Cereals Trust; SMRI; Novartis; Pfizer; DRI;PATH; L’Oreal; Afriplex; Nestle Small companies, eg Resyn, Kappa, Xsit, Inqaba, etc

  6. Systems approach • Coordination: awareness, national objectives, teamwork and cooperation/collaboration • Strategic programmes to provide emphasis in priority areas • System support initiatives (HCD, service platforms, IP management, entrepreneur training, pilot scale facilities; Clinical trialing resources, etc) Coordinating committees National use of MRC, ARC, CSIR expertise Techno-feasibility assessments

  7. Opportunity of Bio-innovation √ √ √ √ √ . • In 2014 South Africa’s GDP was R3,8 trillion. • Top 7 DST investee biotech co’s R1 billion turnover. • Need to benchmark current bio-economy (NACI) • US & European bio-economies target 5-6% GDP by 2030 • If SA to reach that, it would form approx R190 billion (today’s terms) .

  8. Challenges of Bio-innovation • Most highly regulated scientific field(s) of endeavour. • Most diversified applications (agric, health, manufacturing, energy, environment, etc). High level coordination is required. • Applications for existing industry AND new industry • Rapidly developing fields (knowledge, equipment, applications). • Some controversy (GE, stem cells & cloning). • The days of single blockbusters are gone. Need for sophistication, contextualisation, personalisation and precision.

  9. Measuring the Bio-economy • Currently developing a ‘metrics’ approach: • High Level Impacts: • Sophistication of products • Exports of technology products • Unit value of exports • Outcomes per theme (economic, social, environmental) • Eg. Technologies localized; household with food security; medicines developed; revenues generated • Outputs per theme (meeting objectives of themes) • Publications; technologies; patents; companies; products

  10. Cross cutting & ongoing activities of the Department • Cross-cutting initiatives • Public Understanding of Biotechnology (NRF) • Biosafety Communication Platform (TIA) • Bioinformatics and Functional Genomics human capital development (NRF) • Bioinformatics Platform (CHPC/CSIR) • Bio-entrepreneurship training (CSIR/TIA/eGoliBio) • Bioportal development (consortium) • Bio-economy Metrics (NACI) • Platforms • Centre for Proteomic and Genomic Research (TIA) • H3D Human Drug Discovery & Development (TIA) • Metabolomics (TIA) • Bioprocessing (TIA) • Southern African Human Genome Programme (SHIP)

  11. Agroprocessing and Agro-engineering Overview: Agriculture implementation plan Cross cutting initiatives: Agric biotech skills, academic research capabilities, Tech. Serv. platforms, Biosafety capacity, Public awareness, IT & bio entrepreneurship training, Agro-innovation hubs Natural Resource management Indigenous African Knowledge based Agriculture

  12. Key Bio-economy activities of the Department • Agriculture - DST projects: • Eucalyptus Genome Programme (UP + industry) • Wheat pre-breeding platform (Grain SA + consortium) • Feasibility study Agro-innovation hubs (part of agri-parks) • TIA projects (some): • Cassava commercial trials- Limpopo, Mpumalanga + KZN • Microwave egg pasteurizer (CSIR, UP, industry) • Post-harvest biocontrol in table grapes (ARC, CSIR + industry) • Indigenous flower bulbs (ARC) • Sweet stem sorghum as biofuel feedstock (UKZN) • ‘Beochic’ as a growth promoter in poultry (Industry) • AgraChem – fertilizers & biocontrol (Industry)

  13. Overview: Health Implementation Plan New or improved therapeutics & drug delivery New vaccines and other biologicals New or improved diagnostics New medical devices Translational Architecture (ICTs, Knowledge Management, Modelling, Advanced Statistical Analysis) Build the Health Innovation System Development Discovery Product development cycle Dissemination Decision support Market access / Impact monitoring Technology develop-ment Capacities & capabilities Technology & knowledge transfer

  14. Key Bio-economy activities of the Department Health – SHIP projects:

  15. National Enabling RD&I Platforms Priority Areas Biochemicals & Biologics Commodity chemicals Fine Chemicals Pharma-ceuticals Vaccines Biologics Enzymes Bioenergy Heat Electricity Biodiesel Bioethanol Remediation technology Mineral, oil, and salt recovery Sanitation solutions Biomining, Waste & Wastewater Biocomposite Bioplastics Biosynthetic materials Biomaterials Biomanufacturing Bioprocessing Biopharming Biocatalysis Biocomposites BioGROW BioPAC Bioresins Biorefineries Physical Chemical Thermal Biological Biomining, Waste & Wastewater Beneficiation BioMining Water Biorefineries Overview: industry & Environment Implementation Plan

  16. Key Bio-economy activities of the Department • Industry & Environment: • DST projects • Biocatalysis – developing human capital in useful • enzymes (consortium) • Biorefinery modelling and new product development • Water Foot-printing Analysis for SA pulp Mills • From sucrose to high value commodity chemicals • Energy use reduction and monitoring opportunities in sugar factories. • Biomanufacturing Industry Development Centre (CSIR) – supporting industry start-ups. • Pyrolysis of plastic/fibre wastes • TIA • Sweet stem sorghum as biofuel feedstock (UKZN) • Continuous seed preparation for sugar processing (SMRI, TongaatHullet)

  17. Indigenous Knowledge-based Technology Innovation Objective: Mainstreaming IK-based products Institutional Technical >80 community members trained Various communities & knowledge holders involved/participating in validation and prototype development. Economic Social/Cultural

  18. Key Bio-economy activities of the Department • Indigenous Knowledge-based Technology Innovation

  19. Key Bio-economy activities of the Department Capacity building: IKS PhD, MSc and undergraduate students

  20. Key Bio-economy activities of the Department Partnership with University of Limpopo sitting on Limpopo Agro-food Technology Station (LATS)

  21. Key Bio-economy activities of the Department Construction of the Tooseng Processing Facility 15/04/2015 Figure 2: Some of the Moringa related products that have been developed

  22. Key Bio-economy activities of the Department Some of the Moringa related products that have been developed Figure 2: Some of the Moringa related products that have been developed

  23. Way forward: Bio-economy 2015/6 • Implementation plans • Finalization & publication • Presentation to Treasury • Activities • Creation of Coordinating Committees (including govt, science councils, industry, academia) to advise DST on priorities & actions. • Development of R&D support models (similar to SHIP) at the ARC and CSIR. • Techno-feasibility study on Agro-innovation Hubs concluded. • New budget for the Bio-economy required

  24. Some Bio-economy successes • Previously reported: • By 2014, the top 7 biotech companies had a combined annual turnover of nearly R1 billion (from a direct investment of R63million); • Eucalyptus Genome project – already providing cost savings to industry; • Xsit – already providing additional income to the citrus industry; • Umbiflow – providing for better maternal healthcare; • mTriage – better emergency care. • New additions: • 10 IK-Based Cosmeceuticals (anti-acne, anti-eczema, anti-wrinkle, anti-aging, skin toner, moisturisers and sun-screens) are ready for early commercialisation; • Access and benefit sharing agreement entered into with various communities in Gauteng, Northern Cape, Western Cape, and Eastern Cape; • Five new patents filed from IKS technologies.

  25. Ndo livhuwa Enkosi Thank you Baie dankie Siyabonga Re a lebogaHa Khensa Enkosi Ditebo

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