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Summary of Cell Cycle and its Regulation

Summary of Cell Cycle and its Regulation. AP Biology. Review of Cell Cycle. Sample Question. If the S phase were eliminated from the cell cycle, the daughter cells would Have half the genetic material found in the parent cell Be genetically identical to each other

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Summary of Cell Cycle and its Regulation

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  1. Summary of Cell Cycle and its Regulation AP Biology

  2. Review of Cell Cycle

  3. Sample Question • If the S phase were eliminated from the cell cycle, the daughter cells would • Have half the genetic material found in the parent cell • Be genetically identical to each other • Be genetically identical to the parent • Synthesize the missing genetic material on their own

  4. Sample Question • Select from one of the choices that best fits the description • Telophase • Interphase • Cytokinesis • Prophase • Anaphase Descriptions • Cytokinesis during this final stage of mitosis • Division of cytoplasm • Sister chromatids separate • Genetic material replicates

  5. Checkpoints

  6. Sample Questions • After which of the following checkpoints in the cell cycle is the cell first committed to divide? • G2 checkpoint • M checkpoint • Interphase checkpoint • G1 checkpoint • MPF checkpoint

  7. Maturation Promoting Factor (MPF) • Composed of cyclin bound to a cyclin dependent protein kinase • CDK • constant concentration • Active only when bound to cyclin • Cyclin • Concentration varies during the cell cycle

  8. Changes in CyclinConcentration

  9. Practice Problem • Look at Figure 7.9 in your handout and read through the investigation • What was the purpose of radioactive labeling • Why would you expect more radioactive labeling of DNA during S phase • What were the percentages of cells in S phase in each of three experiments provided? • What does that suggest in terms of control of cell cycle?

  10. Questions?????

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