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BASIC AND CLINICAL RESEARCH LINKS

BASIC AND CLINICAL RESEARCH LINKS. Romulo S. de Villa, MD, PhD Molecular & Nutritional Oncologist Professor of Biochemistry & Nutrition, FEU-NRMF Molecular Biology & Biotechnology Consultant. Overview of Medical Research (Basic & Clinical). A Scientific Investigation to

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BASIC AND CLINICAL RESEARCH LINKS

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  1. BASIC AND CLINICAL RESEARCH LINKS Romulo S. de Villa, MD, PhD Molecular & Nutritional Oncologist Professor of Biochemistry & Nutrition, FEU-NRMF Molecular Biology & Biotechnology Consultant

  2. Overview of Medical Research (Basic & Clinical) • A Scientific Investigation to • understand the disease process • develop new and improve existing • diagnostic tools • (clinical testing for validity, accuracy & precision) • treatment (prophylactic & therapeutic) • (clinical testing for ) • Understand the disease process by observing • patient (clinical & community) • tissue laboratory • cellular laboratory • molecular laboratory

  3. Basic science will develop: tools of diagnosis agents for treatment Clinical medicine will test: tools of diagnosis agents for treatment Understand Disease Mechanism

  4. Understanding the Disease Process • Epidemiologic identification of causative agent or factor and • Critical analysis of clinical course • Biochemical and Physiologic Mechanisms of the disease at the following levels: • tissue • cellular • molecular

  5. Developing and ImprovingDiagnostic Tools • Developing laboratory procedures • detect the difference in a sick individual • indicated by results of • biochemical and physiologic investigation of disease mechanism • Improving laboratory procedures • utilize new more sensitive, more specific technologies • (Clinical Testing: to determine accuracy)

  6. Developing and ImprovingTreatment • Developing agents and procedures that: • reduce the risk of developing the disease • modify or affect biochemical and physiologic mechanisms of the disease that will: • diminish clinical manifestations • prevent recurrence • reduce risk of death from the disease • (Clinical/Community Trial: to determine effectiveness)

  7. Thank You !

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