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Searching Patents on STN

Searching Patents on STN. OTHERS. IFI. CA FILES. DERWENT. Results. Marpat (Prev.). HCAPlus (PATIPC). ANs (subset). Pn,Apps,keywords. RESULTS. Wpindex (DCR). Wpids (FC-MC). Structures. RNs. ICC. (only subscribers). Registry. keywords. keywords. Others. RESULTS. RNs. RNs.

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Searching Patents on STN

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  1. Searching Patents on STN

  2. OTHERS IFI CA FILES DERWENT Results

  3. Marpat (Prev.) HCAPlus (PATIPC) ANs (subset) Pn,Apps,keywords RESULTS Wpindex (DCR) Wpids (FC-MC) Structures RNs ICC (only subscribers) Registry keywords keywords Others RESULTS RNs RNs Ifiudb keywords keywords keywords DUP. IDE. FSORT RESULTS USPat. (it,ti,st,clm,ab) RESULTS keywords FINAL RESULTS keywords NCL Uniterms, NCL Ifiref Citations keywords, NCL Patents search flow-sheet

  4. In a typical search in STN you use two main concepts: • Substance Identifiers • Functionality Identifiers

  5. Substance Identifiers A = RNs, CTs, DCRs, DCNs, UNs, Markush (Code Fields) B = Chemical Names, CTs/Bi (Basic Index)

  6. Substance Identifiers Find A and B for this compound

  7. Substance Identifiers => fil reg => oc4/es(p)c6/es(p)cnrs=>2 and c h o s/elf and furanon? and nc=1 and ?sulfon?/cns L1 738 OC4/ES(P)C6/ES(P)CNRS=>2 AND C H O S/ELF . . . . => sel rn L2 SEL L1 1- RN : 738 TERMSA = RNs

  8. Substance Identifiers => sel l6 name L7 SEL L6 1- NAME : 29 TERMSB = Names/bi TERM # # OCC # DOC % DOC NAME ------ ------- ------ ------ --------------- 1 1 1 0.14 (R)-(-)--TOSYLOXY--BUTYROLACTONE 2 1 1 0.14 (R)-(-)-DIHYDRO-5-(((P-TOLYLSULFONYL)OXY)METHYL)-2( 3 1 1 0.14 (S)-(+)--TOSYLOXY--BUTYROLACTONE 4 1 1 0.14 (S)-(+)-DIHYDRO-5-(((P-TOLYLSULFONYL)OXY)METHYL)-2( 5 1 1 0.14 (S)-5-(((4-(1-ETHYL-1-(3-METHYL-4-((2-METHYLPROPAN- 6 1 1 0.14 CIS-3-METHYL-6-(P-TOLUENESULFONYLOXY)HEXAN-4-OLIDE 7 1 1 0.14 DFP 8 1 1 0.14 DIHYDRO-5-((((4-METHYLPHENYL)SULFONYL)OXY)METHYL)-2 9 1 1 0.14 EQUIXX 10 1 1 0.14 FIROCOXIB 11 1 1 0.14 LIBRENS 12 1 1 0.14 MATAIRESINOL DIMESYLATE 13 1 1 0.14 MK 0966 14 1 1 0.14 MK 966 15 1 1 0.14 ML 1785713 16 1 1 0.14 NSC 178878 17 1 1 0.14 NSC 605543 18 1 1 0.14 ROFECOXIB 19 1 1 0.14 VIOXX 20 1 1 0.14 2(3H)-FURANONE, DIHYDRO-3-(DIPHENYLSULFONIO)-, YLID 21 1 1 0.14 2-PHENYLSULFONYL--BUTYROLACTONE 22 1 1 0.14 2,2-DIMETHYL-4-(PHENYLSULFONYL)METHYL-3(2H)-FURANON 23 1 1 0.14 3-(BENZENESULFONYLOXYMETHYL)-5,5-DIMETHYLDIHYDRO-2( 24 1 1 0.14 3-(4-METHANESULFONYLPHENYL)-2-PHENYL-2-BUTEN-4-OLID 25 1 1 0.14 3-PHENYL-4-(4-(METHYLSULFONYL)PHENYL)-2(5H)-FURANON 26 1 1 0.14 4-((4-METHYLSULFONYL)PHENYL)-3-PHENYL-2(5H)-FURANON 27 1 1 0.14 4-(3-BENZYLOXY-4-PROPOXY-5-PROPYLSULFONYLPHENYL)BUT 28 1 1 0.14 4-(4-(METHANESULFONYL)PHENYL)-3-PHENYL-5H-FURAN-2-O 29 1 1 0.14 5,5-DIMETHYL-3-(TOSYLOXYMETHYL)DIHYDRO-2(3H)-FURANO

  9. Substance Identifiers => sel l6 name L7 SEL L6 1- NAME : 29 TERMSB = Names/bi The name search can be selective with the command: => S L7 <nx , nk , nj – nz>

  10. Substance Identifiers => fil ifiref => l7 L8 1 L7 => sel l8 un L9 SEL L8 UN: 1 TERMSA = UN

  11. Substance Identifiers => fil wpindex => Uploading C:\Program Files\stnexp\Queries\dcr.str L1 STRUCTURE UPLOADED => d

  12. Substance Identifiers => l1 FULL FILE PROJECTIONS: ONLINE **COMPLETE** BATCH **COMPLETE** PROJECTED ITERATIONS: 173 TO 527 PROJECTED ANSWERS: 66 TO 334 L2 20 SEA SSS SAM L1 => l1 full L4 172 SEA SSS FUL L1A = DCRs

  13. Substance Identifiers

  14. Substance Identifiers => sel name 'NAME' IS NOT A VALID FIELD CODE FOR FILE 'WPINDEX => sel cn L5 SEL L4 1- CN:14 TERMSB = Names/bi => sel l4 sdcn L6 SEL L4 1- SDCN:172 TERMSA = SDCNs/DCN

  15. Substance Identifiers => fil reg => oc4/es(p)c6/es(p)cnrs=>2 and furanon? and ?sulfon?/cns L1 1514 OC4/ES(P)C6/ES(P)CNRS=>2 AND . . . . . . . => fil caplus => l1 and marpat/os L2 364 L1 AND MARPAT/OS => fil marpat => l2 L3 364 L2

  16. Substance Identifiers

  17. Substance Identifiers . . . . . . . . . . . . isolated ring systems : containing 1 : Match level : 1:CLASS 2:CLASS 3:CLASS 4:CLASS 5:CLASS 6:CLASS 7:CLASS 8:CLASS 9:CLASS 10:CLASS 11:CLASS 12:CLASS 13:CLASS 14:CLASS 15:CLASS 16:CLASS 17:CLASS UNLIMITED L4 STRUCTURE UPLOADED

  18. Substance Identifiers => l4 full subset=l3 L6 152 SEA SUB=L3 SSS FUL L4 G4 = heterocycle <containing zero or more N, zero or more O, zero or more S, 1 or more double bonds> (substd. by G5)

  19. Substance Identifiers => fil caplus => l6 L7 152 L6 A = Markush Strutures

  20. Functionality Identifiers A’ = CTs, NCL, IC, UNs, Roles (Code Fields) B’ = Keywords, CTs/Bi (Basic Index)

  21. Functionality Identifiers Find A’ and B’ for the following concept: antitumor agents

  22. Functionality Identifiers => fil hcaplus => e antitumoral agents/ct => e e5+all => e e14+all => e17+old,nt L1 195337 "ANTITUMOR AGENTS"+OLD,NT/CTA’ = CTs => e17-50/bi L2 215139 ("ANTITUMOR AGENTS"/BI OR .B’ = CTs/Bi

  23. Functionality Identifiers => fil ifiref => e17-50/bi L3 58 ("ANTITUMOR AGENTS"/BI OR . . . . . . . . . => l3 and class/fs L4 0 L3 AND CLASS/FS => l3 and general/fs L5 55 L3 AND GENERAL/FS => sel 1-55 un L6 SEL L5 1-55 UN : 55 TERMSA’ = Uniterms

  24. Functionality Identifiers => (tumor or tumour) and class/fs L7 3 (TUMOR OR TUMOUR) AND CLASS/FS => sel ncl L8 SEL L7 1- NCL : 3 TERMSA’ = NCL

  25. Functionality Identifiers => fil patipc => e17-50/bi L9 1 ("ANTITUMOR AGENTS"/BI OR . . . . . . . . . . . => (anti-tumor? or anti-tumour? or antitumor? or antitumour? or antineoplastic? or anti-neplastic?) L10 1 (ANTI-TUMOR? OR ANTI-TUMOUR? OR . . . . . => sel l9 ic7mg len 7 L10 SEL L9 1- IC7MG LEN 7 : 1 TERMA’ = IC

  26. Combinations • Substance Identifiers Functionality Identifiers • A (Code Fields) AND/L A’ (Code Fields) • A (Code Fields) AND/L B’ (Basic Index) • B (Basic Index) AND/L A’ (Code Fields) • B (Basic Index) AND/L B’ (Basic Index)

  27. General Searches (A or B) and/l (A’ or B’) splitted in A(and/l)A’ or A(and/l)B’ or B(and/l)A’ or B(and/l)B’ with this search you get the maximum of results but also the maximum of false drops (only two terms must be present)

  28. General Searches (A and B) and/l (A’ and B’) splitted in A(and/l)A’ and A(and/l)B’ and B(and/l)A’ and B(and/l)B’ with this search you get the minimum of results but also the minimum of false drops (all terms must be present)

  29. General Searches (A or B) and/l (A’ and B’) splitted in A(and/l)A’ and A(and/l)B’ or B(and/l)A’ and B(and/l)B’ this is the most popular search (three terms must be present)

  30. CASE STUDY

  31. Find patents concerning the use of Zyprexa for the treatment of appetite disorders

  32. Substance Identifiers ZYPREXA

  33. Functionality Identifiers appetite disorders

  34. Marpat (Prev.) HCAPlus (PATIPC) ANs (subset) Pn,Apps,keywords RESULTS Wpindex (DCR) Wpids (FC-MC) Structures RNs ICC (only subscribers) Registry keywords keywords Others RESULTS RNs RNs Ifiudb keywords keywords keywords DUP. IDE. FSORT RESULTS USPat. (it,ti,st,clm,ab) RESULTS keywords FINAL RESULTS keywords NCL Uniterms, NCL Ifiref Citations On the basis of this flow sheet develop a strategy, on paper. Run some preliminary searches, and try to write some search strings, using A, A’, B, B’. keywords, NCL Patents search flow-sheet

  35. Search Stategy 1° Step: RNs, Chemical Names, Markush structures, and, CTs, Keywords, NCLs, ICs 2° Step: RNs, UNs, Chemical Names, and , Keywords, NCLs, UNs 3° Step: Chemical Names, Derwent codes, and, IC, Keywords 4° Step: Other Files 5° Step: Final Results

  36. Search Summary 1° Step: RNs or Chemical Names and CTs or ICs or NCLs or Keywords Files involved: Registry, HCAplus, Marpat,Usan, Chemcats, Drugpat, Mrck, Uspatfull

  37. Search Summary Collecting: A = RNs, Markush B = Chemical Names A’ = CTs, ICs, NCLs B’ = Keywords Substance Functionality Searching A(and)A’ or A(l)B’ or B(and)A’ or B(l)B’

  38. Search Summary Collecting A = RNs

  39. Registry

  40. Registry ZYPREXA

  41. Registry Ring System Data Elemental | Elemental | Size of |Ring System| Ring | RID Analysis | Sequence |the Rings| Formula |Identifier|Occurrence EA | ES | SZ | RF | RID | Count ===========+=============+=========+===========+==========+========== C4N2 |NC2NC2 |6 |C4N2 |46.383.1 |1 C4S-C6-C5N2|SC4-C6-NC2NC3|5-6-7 |C11N2S |2515.92.2 |1

  42. Registry Search by Structure and Dictionary

  43. Registry Isolated/embedded rings

  44. Registry L1 STRUCTURE UPLOADED => l1 full L4 649 SEA L1 FULL A = RNs => sc4/ess(s)c6/ess(s)nc2nc3/ess(p)nc2nc2/ess L5 854 SC4/ESS(S). . . . A = RNs => l5 not l4 L6 205 L5 NOT L4 => l4 not l5 L7 0 L4 NOT L5

  45. Registry

  46. Search Summary Collecting B = Chemical Names

  47. Registry Usan Chemcats Drugpat Mrck

  48. => index registry chemcats usan drugpat mrck => zyprexa/cn 1 FILE REGISTRY 941 FILE IMSPATENTS 1 FILE MRCK L8 QUE ZYPREXA/CN => fil hit

  49. => fil hit => l8 L12 943 L8 => sel name L13 SEL L12 1- NAME :15 TERMSB = Chemical Names => d 1-15

  50. TERM # # OCC # DOC % DOC NAME ------ ------- ------ ------ --------------- 1 942 942 99.89 LY 170053 2 942 942 99.89 ZYPREXA 3 941 941 99.79 ZYPREX 4 528 528 55.99 OLANSEK 5 413 413 43.80 OLANZEK 6 318 318 33.72 OLANZAPINE 7 286 286 30.33 OLANZAPINE FORM II 8 212 212 22.48 OLANZAPINE EMBONATE 9 212 212 22.48 OLANZAPINE PAMOATE 10 127 127 13.47 OLANZAPINE DIHYDRATE 11 74 74 7.85 SYMBYAX 12 1 1 0.11 ***ZYPREXA*** 13 1 1 0.11 LANZAC 14 1 1 0.11 LY-170053 15 1 1 0.11 2-METHYL-4-(4-METHYL- . . . B = Chemical Names

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