1 / 4

Influenza A/H1N1 W. Rose 20091026 H1N1 is a subtype of influenza type A

Influenza A/H1N1 W. Rose 20091026 H1N1 is a subtype of influenza type A Influenza types B and C also exist but less common, less infectious, and drift less rapidly than type A

edwardjones
Télécharger la présentation

Influenza A/H1N1 W. Rose 20091026 H1N1 is a subtype of influenza type A

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Influenza A/H1N1 W. Rose 20091026 H1N1 is a subtype of influenza type A Influenza types B and C also exist but less common, less infectious, and drift less rapidly than type A Drift: gradual change in properties due to relatively rapid mutation rate (due to lack of proofreading of RNA polymerase product) Reassortment: combinations of genes from different viruses in a multiply-infected cell

  2. http://medicineworld.org/images/blogs/9-2006/influenza-virus-82101.jpghttp://medicineworld.org/images/blogs/9-2006/influenza-virus-82101.jpg • Parts of virus • Membrane with glycoproteinshemagglutinin (H), neuraminidase (N); ion channels (M2) • Capsid (protein shell) • Ribonucleoproteins (ssRNA, RNA polymerase, etc)

  3. Influenza A/H1N1 life cycle • http://www.xvivo.net/zirus-antivirotics-condensed/ • How it enters the cell • What it does there • How it reproduces

  4. Influenza Vaccines • Seasonal Flu Vaccine • Mix of two A types, one B type • Injectable: killed (inactivated) virus • Nasal spray: live attenuated • H1N1 2009 Flu Vaccine • Injectable: killed (inactivated) virus • Nasal spray: live attenuated • Antiviral treatment • Oseltamivir (Tamiflu), zanamivir (Relenza) : neuraminidase inhibitors, blocks viral budding from cell • Amantadine etc.: blocks M2 ion channel, thus preventing uncoating; resistance common

More Related