1 / 5

APOPTOSIS

APOPTOSIS. Apo: apart Ptosis: falling Shedding of leaves from trees!. Characteristics of Apoptosis. Shrinks. Blebbing. Nucleus breaks down, breaks into small membrane wrapped fragments. Importance of Apoptosis. Maturing organisms. Viruses. Immune System. DNA damage. What is a Caspase?.

elwyn
Télécharger la présentation

APOPTOSIS

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. APOPTOSIS Apo: apart Ptosis: falling Shedding of leaves from trees!

  2. Characteristics of Apoptosis • Shrinks. • Blebbing. • Nucleus breaks down, breaks into small membrane wrapped fragments.

  3. Importance of Apoptosis • Maturing organisms. • Viruses. • Immune System. • DNA damage.

  4. What is a Caspase? • Have been termed "executioner" proteins for their roles in the cell. • Plays an essential role in apoptosis, necrosis, and inflammation. • Two types of caspases; initiator (2,8,9,10) & effector caspases (3,6,7). • CASP 4,CASP 5 are not classified as initiator nor effector because they are inflammatory enzymes that, with the help of CASP 1,are involved in T-cell maturation.

  5. Apoptosis: Pathways Death Receptors Initiator Caspase 8 Effector Caspase 3 PCD Initiator Caspase 9 Mitochondria/Cytochrome C “Extrinsic Pathway” Death Ligands “Intrinsic Pathway” DNA damage & p53

More Related