1 / 36

In the name of God

In the name of God. Hydrops Fetalis. Hydrops = Generalized subcutaneous edema in the fetus or neonate. Definition : Excess serous fluid in at least one space (ascites, pleural effusion, or pericardial effusion) + skin edema (> 5 mm thick) Excess fluid in two spaces without edema.

Télécharger la présentation

In the name of God

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript


  1. In the name of God

  2. Hydrops Fetalis

  3. Hydrops = Generalized subcutaneous edema in the fetus or neonate

  4. Definition : • Excess serous fluid in at least one space (ascites, pleural effusion, or pericardial effusion) + skin edema (> 5 mm thick) • Excess fluid in two spaces without edema

  5. Immune Hydrops Fetalis (10%) Hydrops Fetalis Non Immune Hydrops Fetalis (90%)

  6. Pathogenesis • Anemia • Cardiac failure • Fetal Hypoxemia

  7. Pathogenesis (cont). • Extra vascular protein leakage → increased capillary permeability → hypoalbuminemia → Accumulation of fluid in body cavities • Placental perfusion abnormalities

  8. Etiology • Hematologic: Due to anemia (10% of cases) : • Isoimmune hemolytic disease (RH incompatibility). • Hemozygous alphathalassemia • Hemozygous G6PD d, • Feto maternal hemorrhage - twin - to twin transfusion • Bone marrow failure - bone marrow replacement - leukemia

  9. In RH incompatibility : • Fetus is RH + / mother is RH – • Maternal exposure to foreign antigens → IgG antibodies fetal antigens → destruction of fetal RBCs → Hemolysis hydrops fetal anemia → reticulocytosis (Hb<7 g/dL)→ erythroblastosis. Against In severe form In moderate form In severe form

  10. Cardiovascular: Due to heart failure (20% cases) • Rhythm disturbances • Major cardiac disease

  11. Renal (5% of cases) Nephrosis, RVT, urinary obstruction

  12. Infection (8% of cases) TORCH-Syphilis-Congenital Hepatitis, Parvovirus….

  13. Pulmonary (5% of cases) Chylothorax, diaphragmatic hernia , intrathoracic mass

  14. Placental or cord (rare)

  15. Maternal conditions (5% of cases) : Toxemia, diabetes, thyrotoxicosis

  16. Gastrointestinal (5% of cases) : Meconium peritonitis …..

  17. Chromosomal (5% of cases) : Turner syndrome, trisomy 13,18,21

  18. Miscellaneous (10% of cases) : Cystic hygroma, wilms’ tumor – teratoma - Neuroblastom

  19. Unknown (20% of cases) :

  20. Signs of hydrops : • Pericardial & pleural effusions • Ascites • Skin edema • Hepatosplenomegaly • Polyhydramnios • Placental thickening

  21. Diagnosis : • Pregnant woman with : • Polyhydramnios, severe anemia, toxemia, isoimmune disease → ultrasonic examination → Fluid accumulation in the fetus or placenta of circulating maternal antibody → NIHF In the absence

  22. Post natal Evaluation

More Related