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RISK FACTORS IN CADAVERIC DONORS OF LIVERS PROCURED FOR ELECTIVE AND URGENT RECIPIENTS

RISK FACTORS IN CADAVERIC DONORS OF LIVERS PROCURED FOR ELECTIVE AND URGENT RECIPIENTS. Edyta Karpeta 1 , Jarosław Czerwiński 2,3 , Dariusz Wasiak 2 , Piotr Małkowski 2 , Andrzej Chmura 1 1 Department of General and Transplant Surgery, Medical University of Warsaw

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RISK FACTORS IN CADAVERIC DONORS OF LIVERS PROCURED FOR ELECTIVE AND URGENT RECIPIENTS

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  1. RISK FACTORS IN CADAVERIC DONORS OF LIVERS PROCURED FOR ELECTIVE AND URGENT RECIPIENTS Edyta Karpeta1, Jarosław Czerwiński2,3, Dariusz Wasiak2, Piotr Małkowski2, Andrzej Chmura1 1Department of General and Transplant Surgery, Medical University of Warsaw 2Department of Surgical and Transplant Nursing, Medical University of Warsaw 3Polish Transplant Coordinating Centre Poltransplant

  2. Introduction & Objectives Liver procurement from non-standard donors has become justified and it may have specific reasons in cases of recipients who await for urgent transplantations. On the other hand, it is known that for such recipients the results are better when organs are obtained from ideal not expanded-criteria donors. The aim of this study was to compare the characteristics of cadaveric donors whose livers were used in elective versus urgent transplantations for the purpose of assessment if indeed the differences exist in the biological quality of organs for these two groups of recipients.

  3. Materials & Methods • Characteristics of 582 cadaveric liver donors and of recipients who received organs from these donors in the years 2006-2008were analyzed. • Donors and recipients were divided into two groups of transplantations: • elective – 387 • urgent – 195 • For the purpose of the study 12 donor related factors were analyzed:

  4. Materials & Methods • Two methods were used for calculation if the two groups of liver donors differed in the matter of clinical risk factors which would have possible impact on post-transplant function: • the comparison of frequency of particular risk factor incidence in both groups, • the comparison of the average number of risk factors documented in the group of liver donors for elective and in the group of donors for urgent recipients. • Chi-squared test and T-test were used for statistical analysis; • p value of <0.05 was considered as statistically significant.

  5. Results: Frequency of donor risk factor incidence

  6. Results: Mean number of risk factors

  7. Conclusions In almost all cases of liver transplantations (94%) donor related risk factors are accepted The criteria of cadaveric liver donors are not different in the group of donors for elective versus urgent recipients; biological characteristics of transplanted organs are comparable in both groups The tendency to expand donor criteria for urgent recipients is not observed

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