Enabling Technology Innovation in Healthcare and the Life Sciences

1. HST.921 HST.922 HST.923 HST.924 Spring 2014 Enabling Technology Innovation in Healthcare and the Life Sciences Mirena Bagur Course Co-Director Steven Locke, MD Course Co-Director Bryan Bergeron, MD Assistant Directors Chandrika Samarth, MBA Course Fellow

2. Agenda • Course Mission Statement • Course Overview • Faculty, Students, and Sponsors • Lectures • Tutorials • Practicum – Projects and Final presentations • FAQs • Registration & Credit • Q&A • Contact

3. HST.921: Enabling Technology Innovation in Healthcare and the Life Sciences http://hst921.org Lectures: Tuesdays, 4:00-5:30pm Tutorials/Lab: Tuesdays, 5:45-7:00pm Place: MIT E51-151 Classes start Tuesday, Feb 4th

4. Mission Statement To empower students to: critically analyze a current -- or future -- problem in health care and the life sciences, and working in teams, develop a novel solution using information technologies.

5. Course Faculty Steven Locke, MD Research Psychiatrist, Division of Clinical Informatics Beth Israel Deaconess Medical Center  Associate Clinical Professor of Psychiatry, Harvard Medical School Affiliate Faculty, Division of Health Sciences and Technology, MIT Mirena Bagur CONTeXO Group The Capital Network MIT Enterprise Forum MTLC Affiliate Faculty, Division of Health Sciences and Technology, MIT Bryan Bergeron, MD President, Archetype Technologies Assistant Professor of Health Sciences and Technology, MIT Chandrika Samarth, MBA Course Fellow Director of research at a grant funded start up

6. Industry Mentors • Winfried A. Burke • CEO, iGetBetter; serial entrepreneur/software • Francis X. Campion, MD • Vice President of Clinical Affairs, Alere Analytics • Diplomate, Clinical Informatics, American Board of Preventive Medicine • Renu Chipalkatti • Executive Director, Healthcare and Incubation @ Verizon Enterprise Solutions • Greg Erman • CEO, lecturer, serial entrepreneur, med devices • Mark Hauser, MD • OnSite Psychiatric Services

7. Expert Panelists • Daniel Sands, MD Change Agent in Doctor Patient Comm • Lynne Dunbrack Analyst, IDC – Health Industry Insights • David Judge, MD CIMIT • Craig Schneider, Ph.D Mass Health Data Consortium • Al Lewis, JD Founding President, DMAA • Christian Cortis Partner, ATVentures • Anita Goel, MD, Ph.D CEO, Nanobiosym • Deb Theobald CEO, VECNA • Richard Anders Investor, Mass Medical Angels • Peter Lomedico Juvenile Diabetes Foundation • Josh Feast CEO, Cogito Health • Stan Nowak CEO, SilverLink • Michael Lemnitzer Philips Telehealth

8. Student Comments "HST921 was an incredible experience for me. It was an excellent opportunity to meet face-to-face with recognized leaders in the field who are working on really difficult problems and willing to mentor students who are interested in getting involved. HST921 is both an industry overview and an entrepreneurship class in one - which was exactly what I was looking for.” -- Krishna Yeshwant, Harvard MD/MBA 2009 2008 MIT $100K Competition winner and 2008 Harvard Biz School Competition winner

9. Students Harvard • HMS • HSPH • HBS • KSG • HGSE • FAS • HLS • Affiliated hospitals MIT • HST • Computer Science • Electrical Engineering • Biomedical Engineering • Media Lab • Sloan School

10. Sample lectures & tutorials

11. Projects & Final Presentation

12. Group Design Projects • Student driven • Corporate partner driven • Multidisciplinary teams • Tracks • Design, Business, Marketing, Trials • Class exercises (design, elevator pitch) • Group final presentations and paper

13. Common Elements • Objective of the group project • Proposed product or service solution • Industry summary • Analysis • Problems with current solutions • Competitive analysis • Porter model • Evaluation of macro-industry forces • Micro-stakeholder analysis • Interaction diagrams • Reflection on cost, quality, and access

14. Project Track Selection • Track 1: Marketing Analysis • Track 2: Business Plan • Track 3: Product Design Plan • Track 4: Clinical Trial/Product Evaluation Each team chooses two out of four

15. Market Analysis and Plan • Market Background • Future Directions of Market • Market Size/Forecast • Customers/Customer Segmentation • Target Market Segments • Product Description • Pricing • Promotion • Sales and Distribution Strategy

16. Business Plan • Partnering • Staffing Plans • Advisory Board • Risk Management ( analysis of specific risks and address various scenarios ) • Financial Projections and Resources Required • Near Term Milestones and Expenses • Long Term Projections

17. Product Design User Profile • Job Description • User Skills, Knowledge and Education • Work Style • Concerns • Wants • Requirements • Work Environment The Product • Product Definition and Goals • Product Requirements/ Specifications • Expected Product Lifecycle • Product Add-ons, Third Party Tool Sets • Follow-on Products

18. Clinical Trial • Rationale • Objectives • Study design and hypotheses • Participants • Intervention • Primary and secondary endpoints • Sample size (optional) • Anticipate time frame for study completion • Data collection; sub-protocols, intervals, encounters, events • Analysis

19. Sample Student Projects • Student provided project: MedGenuity - Engineering a Premium Platform for Providers • Dossia Consortium -Evaluating the Proposition for PHR: Strategic Analysis & Product Evaluation • Intel - Medication Adherence 2.0 • Insurance Company - Exploration of social networking technologies to engage health care consumers • Symantec - Utilizing the latest technology to easily and securely view & share diagnostic images and reports • J&J - Empowering Consumers and Physicians via Consumer-led Social Media Networks • Healthways - Improving Physician Engagement Through Technology • Careplace - Online Health Consumer Empowerment, Advocacy, and Support • Technology Opportunities in Healthcare for the Baby Boomer Generation • Computer-Assisted Disease Management to Improve Outcomes in Diabetic Patients

20. Sponsors:

21. Student Comments “HST.921 unified business, science, and medicine with a set of uncommon learning objectives, focused on developing skills on how to pursue ideas and get things done in the real world. The curriculum was phenomenal. Best of all, I met some very talented classmates and teachers with whom I share ideas on a frequent basis. Two thumbs up!” Eugene Chan, MD Physician-Innovator-Entrepreneur Director/The DNA Medicine Institute

22. FAQ’s • Project selection • Required readings • Required paper • School-specific credit • Work load • Attendance • Professional standards • Course auditing

23. Registration and Credits MIT Students Go to WebSIS (student.mit.edu) and follow links to pre-registration. Add HST.921 and HST.923 to your pre-registration. Harvard Students https://crossreg.harvard.edu/OASIS/CrossReg/ Cross-Registration Credit Calculator https://crossreg.harvard.edu/OASIS/CrossReg/credit.jsp

24. Registration Credits *can arrange as independent study for credit

25. Questions and Discussion

26. Workshop https://www.leapmotion.com/

27. Workshop = 45 minutes • Two teams • Each define their idea of how LeapMotion can be used in healthcare or life sciences – 20 min brainstorm • Answer these questions: • What does the product do? • How will you make money on the product? • How will you get the money to create a business that will develop the product? • One member of the team presents the group’s answers in about 5 min • Follow-up conversation – 20 min

28. HST921: Contact Info • MirenaBagur • 617-835-5019 • mirena.bagur@gmail.com