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Cell Membrane. Haixu Tang School of Informatics. Membrane Lipids Are Amphipathic Molecules. hydrophilic and hydrophobic molecules interact differently with water. Packing arrangements of lipid molecules. The spontaneous closure of a phospholipid bilayer. Phospholipid mobility.
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Cell Membrane Haixu Tang School of Informatics
hydrophilic and hydrophobic molecules interact differently with water
The other composition of membraneCholesterol and glycolipids It inhibits possible phase transitions: (1) decreases the permeability of the bilayer to small water-soluble molecules; (2) prevents the hydrocarbon chains from coming together and crystallizing.
The asymmetrical distribution of phospholipids and glycolipids
Using hydropathy plots to localize potential a-helical membrane-spanning segments
SDS polyacrylamide-gel electrophoresis pattern of the proteins in the human red blood cell membrane
Three major ways of proteins association with membranes • Noncovalently Associated with the Cytosolic Side: Spectrin • Extends Through the Red Blood Cell Lipid Bilayer as a Single a Helix: Glycophorin • Multipass Membrane Protein: Band 3 protein
Band 3: Anion Transporter The polypeptide chain (about 930 amino acids long) is thought to extend across the bilayer 12 times.