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甲地孕酮

甲地孕酮. 谢一珂 10301030070. 孕激素的生理及药理作用. 临床应用. 临床运用之避孕. 避孕效果 :99.9% 可避孕 必须坚持服用 需增加顺应性 与其他避孕方法比较 :无显著性差异、 可减弱痛经、月经不调、治疗痤疮 不良反应: 类假孕症状. 性早熟: 女性在 8 岁、男性在 10 岁前开始第二 性征发育。 包括 : 中枢性和外周性性早熟 GnRHa ( 促性腺激素释放激素)及其类似物(目前最常用) 甲地孕酮: 对 FAH 无效且有继发性肾上腺功能减退 知柏地黄丸 & 甲地孕酮: 效果好、经济. 临床应用之女性特发性性早熟.

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甲地孕酮

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  1. 甲地孕酮 谢一珂 10301030070

  2. 孕激素的生理及药理作用

  3. 临床应用

  4. 临床运用之避孕 避孕效果:99.9%可避孕 必须坚持服用 需增加顺应性 与其他避孕方法比较:无显著性差异、 可减弱痛经、月经不调、治疗痤疮 不良反应:类假孕症状

  5. 性早熟:女性在8岁、男性在10岁前开始第二 性征发育。 包括:中枢性和外周性性早熟 GnRHa(促性腺激素释放激素)及其类似物(目前最常用) 甲地孕酮:对FAH无效且有继发性肾上腺功能减退 知柏地黄丸&甲地孕酮:效果好、经济 临床应用之女性特发性性早熟

  6. 治疗乳腺癌和前列腺癌的一个明显副作用:增强食欲,体重增加。治疗乳腺癌和前列腺癌的一个明显副作用:增强食欲,体重增加。 治疗晚期癌症厌食-恶病质,但是…… 对CACS引起的肌肉萎缩有一定作用 肾上腺功能减弱的副作用 甲地孕酮之其他

  7. 参考文献 [1].Bodenner, D., et al., A retrospective study of the association betweenmegestrol acetate administration and mortality among nursing home residents with clinically significant weight loss. Am J Geriatr Pharmacother, 2007. 5(2): p. 137-46. [2].Bulchandani, D., et al., Megestrol acetate-associated adrenal insufficiency. Am J Geriatr Pharmacother, 2008. 6(3): p. 167-72. [3].Delitala, A.P., et al., Primary symptomatic adrenal insufficiency induced by megestrol acetate. Neth J Med, 2013. 71(1): p. 17-21. [5].Argiles, J.M., A. Anguera and B. Stemmler, A new look at an old drug for the treatment of cancer cachexia: Megestrol acetate. Clin Nutr, 2013. [6].马小旭, 中西医结合治疗小儿性早熟. 中国实验方剂学杂志, 2011(3). [7]史惠蓉,复方口服避孕药的避孕效果和依从性.国际生殖健康/计划生育杂志,2007(7)

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