1 / 7

Sickle Cell Anemia

Sickle Cell Anemia. By Alex Lange & Roy Darrah. Inheritance Pattern. Parents can be carriers and show no symptoms of the disease. Sickle Cell Anemia is a autosomal reccesive pattern. Mutations. Mutations in the HBB gene causes Sickle Cell Anemia.

kaz
Télécharger la présentation

Sickle Cell Anemia

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Sickle Cell Anemia By Alex Lange & Roy Darrah

  2. Inheritance Pattern Parents can be carriers and show no symptoms of the disease. • Sickle Cell Anemia is a autosomal reccesive pattern.

  3. Mutations Mutations in the HBB gene causes Sickle Cell Anemia. It consists of four protein subunits, 2 alphaglobins and 2 betaglobins which form a hemoglobin (C,E,S,AS). Hemoglobins bind oxygen in a cell, but amino acids can switch with betaglobins making the cell nonfunctional.

  4. Incidences • Sickle Cell Anemia is most common in people with African, Mediterranean, and Caribbean ancestors. • Sickle Cell Anemia is most common inherited blood disorder in the US, 70-80 thousand Americans have this disorder. • 1 in 500 African Americans and 1 in 1000 Hispanic Americans will have this disorder.

  5. Symptoms • Shortness of breath • Fatigue • Delayed growth in children • Yellowing of the eyes and skin • Cells can get stuck in veins • Organ damage (lungs, kidneys, spleen, brain) • High blood pressure

  6. Treatments • There is no cure to Sickle Cell Anemia except for a bone marrow transplant.

  7. Lifetime Limitations • People can live normal lives • Others should avoid a lot of physical activity due to the lack of oxygen and cells • Stay away from high altitudes • Ryan Clark plays football for the Steelers and he has Sickle Cell Anemia. Even though he struggles with extreme exercises and hypoxia from high altitudes.

More Related