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Source: ECDC report 2011

Source: ECDC report 2011. Meningococcal Disease deadly, disabling, disfiguring. Leading infectious cause of death in children Long-term after effects for 1 in 3 affected Top among illnesses feared by parents Strikes suddenly , mainly healthy children

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Source: ECDC report 2011

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  1. Source: ECDC report 2011

  2. Meningococcal Disease deadly, disabling, disfiguring • Leading infectious cause of death in children • Long-term after effects for 1 in 3 affected • Top among illnesses feared by parents • Strikes suddenly, mainly healthy children • Rapid onset: briefwindow for effective medical treatment • Staggering costs

  3. Septicaemia After effects Meningitis • Deafness • Severe learning impairment • Paralysis, plegia • Blindness • Epilepsy • Psychosocial problems • Amputations • Skin, muscle damage • Distorted bone growth • Arthritis • Kidney damage • Cognitive problems • Psychosocial problems

  4. Septicaemia Costs of severe cases Meningitis • Acute medical costs • Long-term medical costs • Specialist equipment • Special education • Direct social care costs, benefits, lost tax revenue • Acute costs • Outpatient costs, prosthetics, corrective surgery • Specialist equipment • School adaptation and support • Direct social costs, benefits, lost tax revenue £3,038,719 £4,474,427

  5. Litigation costs

  6. Early symptoms resemble mild illnesses ~50% of children sent home by GPs Short window for intervention Most deaths within 24 hours Better antibiotics and management: fatality reduced 2 decades: every new therapeutic drug unsuccessful in clinical trials Limited potential for improved diagnosis and treatment

  7. Impact of Hib vaccine in Ireland Adapted from Guidelines for (HPSC (2012) The early clinical and public health management of bacterial meningitis

  8. Incidence of Meningococcal Disease in Ireland Men C vaccine

  9. Reduction in invasive pneumococcal disease in young children

  10. Prevention is better than cure

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