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Antibiotics and Antiviral Therapy

Antibiotics and Antiviral Therapy. ARIAtlas.org. Global Impact.

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Antibiotics and Antiviral Therapy

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  1. Antibiotics and Antiviral Therapy ARIAtlas.org

  2. Global Impact • Only about one-third of all children under five with suspected pneumonia received an antibiotic in the 68 countries that bear the world’s highest burden of childhood and maternal mortality. Making antibiotics available to children who need them could save as many as 600,000 lives every year.

  3. Global Impact • Drug resistance is one of today’s most pressing public health challenges, especially resistance to the antibiotics used to treat Streptococcus pneumoniae, Haemophilusinfluenzae type b, and tuberculosis, and resistance to the antivirals that once worked against influenza.

  4. Global Impact • Very few new antimicrobials are in the pharmaceutical industry pipeline. Microbes continue to develop resistance to existing drugs, but many companies have stopped developing alternatives because they fear the useful life of new products will be short and the market limited.

  5. As prescriptions for antibiotics increase, so does resistance. Source: ARIAtlas.org, World Lung Foundation 2010

  6. Actions That Make a Difference • There is no “magic bullet” to the problem of drug resistance, which occurs even when antimicrobials are used appropriately and intensifies when they are not. Altering prescribing and drug use practices requires aggressive education, sweeping policy interventions, and rigorous practice guidelines targeted at patients, clinicians, and the general public.

  7. Actions That Make a Difference • National and local policies should bar the sale of antibiotics without prescription, and mechanisms to enforce those policies should be in place. • A long-term sustainable commitment to stimulate antimicrobial research should be guided by leaders in government, medicine, industry, academia and public health. The Infectious Disease Society of America is spearheading the “10 x 20” initiative, a collaborative venture to develop 10 new systemic antibacterial drugs by 2020.

  8. Antibiotic-resistant strains of S. pneumoniae threaten to undermine treatment for pneumonia. Source: ARIAtlas.org, World Lung Foundation 2010

  9. The number of new antibiotics approved for sale in the U.S. is declining. Source: ARIAtlas.org, World Lung Foundation 2010

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