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OM Case Report

OM Case Report. 指導醫師 : 林立民醫師、陳玉昆醫師、陳靜怡醫師 報告者 :Intern K 組 吳郁畇、蔡沛倫、張庭豪、龔立揚 報告日期： 2014.06.24. General data. Name : 蔡 O 萍 Sex : female Age : 36 y/o Native : 台灣 Marital status : single Attending V.S. : 李坤宗 醫師 First visit : 2014.06.03. Chief complaint.

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OM Case Report

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  1. OM Case Report 指導醫師:林立民醫師、陳玉昆醫師、陳靜怡醫師 報告者:Intern K 組 吳郁畇、蔡沛倫、張庭豪、龔立揚 報告日期：2014.06.24

  2. General data • Name : 蔡O萍 • Sex : female • Age : 36 y/o • Native :台灣 • Marital status : single • Attending V.S. : 李坤宗醫師 • First visit : 2014.06.03

  3. Chief complaint • Left cheek swelling over 2 months, and left lower lip numbness for about one year.

  4. Present illness • This 36-year-old female patient suffered from left cheek swelling for two months and left lower lip numbness occasionally in the past one year, so she came to our OPD for further examination and treatment.

  5. Intraoral examination • Site: Tooth 37 mesial aspect to anterior ear area, and from maxilla buccal vestibule to mandible buccal vestibule. • Size:5.0x7.0 cm • Color: Normal mucosa coverage • Surface: Smooth and intact • Consistency: Firm • Shape: Dome, sessile • Palpation: rubbery • Bone expansion: (+) • Tenderness/Pain: (-) • Paresthesia: (+) • Fluctuation (-) • Fixed

  6. Past medical history • Denied any underlying disease • Denied any food or drug allergies • Hospitalization (-)

  7. Past dental history • General routine dental treatment • Orthodontic treatment • Attitude to dental treatment : co-operative

  8. Personal history Risk factor related to malignancy • Alcohol (-) • Betel quid (-) • Cigarette (-) Special oral habits : denied

  9. Radiographic examination

  10. Panorex(2014.06.03) There is a multilocularwell-defined border radiolucencywith partial corticated margin over left mandible angle, with expansion of cortex. Extending from 36 meisalroot to mandible angle, and from 2/3 height of ascending ramus to mandible lower border, measuring approximately 5.0 x 7.0 cm in diameter. Left mandible canal is being pressed down, while mental foramen does not affected by the lesion. Root resorption over tooth 36 distal root and tooth 37 is noted.

  11. Differential diagnosis

  12. Peripheral or Intrabony • Left posterior mandibular area • 5 x 7 cm, dome shape, firm consistency, normal mucosa color • Tenderness (-) • Pain(-) • Lip numbness (+) • Bone expansion(+)

  13. Multilocular radiolucence with bony destruction→ intrabony lesion

  14. Peripheral or Intrabony →intrabony

  15. Inflammation, Cyst or Neoplasm Due to panorex finding: Large multilocular RL destruction lesion →cyst or neoplam

  16. Cyst or Neoplasm

  17. →Non-inflammation cyst or benign tumor

  18. Working diagnosis • Ameloblastoma (conventional type) • Keratocystic odontogenic tumor • Central giant cell granuloma • Odontogenic myxoma

  19. Ameloblastoma

  20. Keratocystic odontogenic tumor

  21. Central giant cell granuloma

  22. Odontogenic myxoma

  23. CLINICAL IMPRESSION Ameloblastoma, acanthomatous type, left mandibular angle to ramus

  24. Treatment plan • 1. aspiration with 19G needle under block anesthesia --> yellowish clear fluid --> culture x I • 2. complicated extraction of tooth 37 and incisional biopsy was done from tooth 37 wound, H-P exam (hard x1 --> tooth 37 x1 ; soft x2 --> wall of lesion x1 ; distal gingiva of tooth 37 x1), N/S irrigation, placed one decompression(Marsupialization) device with suture (1 sitich), gauze packing • 3.check CT scan.

  25. CT (2014.06.09) • An unilocularexpansile lesion of tooth-bearing portion of jaw at left mandibular body (5.7x2.7x3.2 cm) with expansion of cortex, homogeneous tumor matrix and dislodgment of teeth is noted. Small soft tissue nodule was not identified in the neck spaces.Theparanasal sinuses were clear.The orbits appeared unremarkable. • The skull base, including the foramina lacerum and ovale, were not eroded.

  26. HISTO-PATHOLOGIC EXAMINATION

  27. 組織名稱： Mandible, left • 臨床診斷： Odontogenic tumor • 腫瘤代碼： Pathologic diagnosis: Bone, mandible, tooth 37, left, extraction, tooth fragment Gross Examination: Additional report of decalcified hard tissue specimen for section A. Microscopic Examination: Microscopically, it shows tooth fragment in section A.

  28. 組織名稱： Mandible lesion wall; gingiva 37 distal • 臨床診斷： Odontogenic tumor • 腫瘤代碼： Pathologic diagnosis: Bone, mandible lesion wall, left, ameloblastoma, acanthomatus change, Oral cavity, gingiva 37 distal, lower left, incision, minimal histological change Gross Examination: The specimen submitted consists of 2 soft tissue fragments and 1 hard tissue fragment in 3 bottles,measuring up to 1.5 x 1.2 x 1.0 cm in size, fixed in formalin. Grossly, they are light brown and white in color and bony hard and rubbery in consistency. All for section and labeled as follows: Jar 0. A: tooth 37 B:lesion wall (soft) C: distal gingiva 37 Microscopic Examination: The slides contain two identical groups of irregular-shaped soft tissue specimens.Microscopically, it shows ameloblastoma, acanthomatus change in section B, minimal histological change in section C.

  29. Discussion ─Marsupialization

  30. Introduction • = Partsch operation • Create a surgical window in the wall of the cyst • Evacuate the contents • Maintain continuity between cyst and the oral cavity, maxillary sinus, or nasal cavity

  31. Introduction • Cyst is only removed a piece to produce the window → the remaining of the cyst left in situ • Benefits： • Decrease intra-cystic pressure • Promote shrinkage of the cyst and bone fill • Use： • As the sole therapy • As a preliminary step when with enucleation

  32. Indication • When enucleation may cause injury or unnecessary sacrifice • When surgical approach is difficult • Assistance in eruption of teeth • Alternative to enucleation for p’t with ill health • Very large cysts → marsupialization first

  33. Advantages • Simple • Spare vital structures from damage

  34. Disadvantages • Pathologic tissue is left in situ , without thorough histologic examination • p’t inconvenience: the cavity traps food debris irrigate the cavity several times every day with a syringe.

  35. Technique • (Prophylactic adminstration of systemic antibiotics) • Anesthetization • Aspirate comfirms the presumptive diagnosis of cyst • Incision: circular or elliptical  large window(1cm ↑) thin bone v.s. thick bone • Remove a window of liningpathologic examination

  36. Contents of cyst are evacuated • If cystic lining is thick enoughsuture to oral mucosa otherwise, cavity packed with gauze with tincture of bezoin or antibiotic ointment for 10 to14 days

  37. Marsupialization • Rarly used as sole form • In most instances , enucleation is done after Marsupialization . • In dentigerous cyst , no residual cyst may exist to be remeoved once the tooth has erupted into the dental arch. • If futher surgery is contraindicated, marsupialization can be performed alone without future enucleation. The cavity may or may not obliterate totally

  38. Enucleation after marsupialization

  39. Introduction • Enucleation is frequently done after marsupialization • Combined approach： • Reduce morbidity • Accelerate complete healing of the defect

  40. Indication • Same as indications listed for marsupialization alone • When the cyst does not totally obliterate after marsupialization • When the p’t find difficult to clean

  41. Advantages • Marsupialization phase: simple procedure that spare adjacent vital structures • Enucleation phase: the entire lesion becomes available for histological examination • The development of a thickened cystic lining  secondary enucleation easier

  42. Disadvantages • The total cyst is not removed initially for pathologic examination. • However, subsequent enucleation may then detect any occult pathologic condition.

  43. Technique • Marsupialization of the cyst • Osseous healing • Cyst decreased to complete surgical removal • Enucleation (when bone is covering adjacent vital structure: prevents injury and jaw fracture)

  44. Technique • common epithelial lining (epithelial bridge)must be removed completely with the cystic lining  an elliptical incision completely encircling the window must be made down to sound bone  stripping the cyst from the window to cystic cavity.

  45. Technique • Cyst enucleated  oral soft tissue must be closed. may require soft tissue flap • cannot close completely  packing (strip gauze and antibiotic ointment). Change repeatedly until granulation tissue has obliterated the opening and epithelial closed over the wound

  46. Marsupialization of unicysticameloblastoma: A conservative approach for aggressive odontogenic tumors

  47. Case 1 • A 17 year-old male patient a painless swelling in the right mandibular premolar region without any sign of sensory impairment • Panoramic view of the patient revealed a well defined radiolucent area extending from the right lateral incisor to the distal root of the first molar tooth

  48. Treatment • Under local anesthesia, an incisional biopsy was performed→ luminal type UA  • The lesion was decompressed between two premolar teeth • Scheduled for radiographic follow-up after an interval of three months

  49. Treatment • Marsupialization • Enucleated with peripheral ostectomy(18months later) • The apical portions of the teeth were resected • Allogenic bone graft material was placed in the cavity

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