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*PROTEINS vs. NUCLEIC ACIDS - PROTEINS : Structural & Functional

*PROTEINS vs. NUCLEIC ACIDS - PROTEINS : Structural & Functional - NUCLEIC ACIDS : Storage of information. The methods : Computational Experimental. The methods : Computational - Ab initio (from principles/from scracht) - Semi-empirical (from experiments) Experimental. The methods :

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*PROTEINS vs. NUCLEIC ACIDS - PROTEINS : Structural & Functional

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  1. *PROTEINS vs. NUCLEIC ACIDS - PROTEINS : Structural & Functional - NUCLEIC ACIDS : Storage of information

  2. The methods: Computational Experimental

  3. The methods: Computational - Ab initio (from principles/from scracht) - Semi-empirical (from experiments) Experimental

  4. The methods: Computational - Ab initio (from principles/from scracht) - Semi-empirical (from experiments) Experimental !!! Interaction of matter with electromagnetic radiation: - EM - X-rays crystallography - NMR - CD

  5. alamethicin

  6. cytochrome c'

  7. RNA-binding protein Rop

  8. cro repressor from phage 434

  9. Interleukin-2,human Growth Hormone, Granulocyte-macrophagecolony-stimulating factor (GM-CSF) andInterleukin-4.

  10. homeodomain binding to DNA.

  11. b-sandwiches

  12. b-barrels porin

  13. SH2 domain

  14. placental ribonuclease inhibitor

  15. Ribonuclease-H

  16. *PROTEINS vs. NUCLEIC ACIDS *UNIQUENESS

  17. *PROTEINS vs. NUCLEIC ACIDS *UNIQUENESS *MOLECULAR RECOGNITION EVENTS

  18. http://www.expasy.org/swissmod/course/text/chapter4.htm http://www.rmn.ub.es http://www.chembio.uoguelph.ca/driguana/NMR/TOC.HTM

  19. INTRODUCTION TO NMR: *The concept of chemical shift *Scalar coupling

  20. Larmor equation: n = g/2p Bo

  21. Nupper -gBo/kT = e Nlower

  22. Larmor equation: n = g/2p Bo

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