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Do Now 2/6

Do Now 2/6. WOD: LANGUID (LANG gwid ) adj. lacking energy; weak; showing little interest in anything. HIGH SCHOOL 7:30 AM 8:35 AM Period 1 or 2 8:40 AM 9:45 AM Period 3 or 4 9:50 AM 10:55 AM Period 5 or 6 11:00 AM 12:00 PM Period 7 or 8 12:00 PM 12:30 PM High School Lunch.

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Do Now 2/6

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  1. Do Now 2/6 • WOD: LANGUID(LANG gwid) adj. • lacking energy; weak; showing little interest in anything HIGH SCHOOL 7:30 AM 8:35 AM Period 1 or 2 8:40 AM 9:45 AM Period 3 or 4 9:50 AM 10:55 AM Period 5 or 6 11:00 AM 12:00 PM Period 7 or 8 12:00 PM 12:30 PM High School Lunch

  2. Chapter 5.2: Cancer INB Pg 37

  3. Cancer • Results from uncontrolled mitosis and cell division • Cells divide repeatedly and a tumor develops • Developed countries: 1 in 4 deaths • more than 200 different forms

  4. Mutations • Cancer starts when mutations occur in the genes that control cell division. • Takes many mutations (not just 1) to cause cancer • Mutated gene called oncogene • Genes mutate regularly, but most mutations are either destroyed by our immune systems or do note survive to undergo mitosis

  5. Mutations • Cancer cells escape are not killed by immune system and survive to reproduce identical daughter cells • By detection, a tumor can contain ~1 billion cancerous cells

  6. Carcinogens • A factor which brings about any mutation is called a mutagen, and is described as mutagenic • Any agent that causes cancer is called a carcinogen, and is described as carcinogenic • Some mutagens are carcinogenic

  7. Carcinogens • Ionizing radiation and UV light • X-rays, gamma rays, radioactive decay, sunlight • Cause formation of damaging ions in cells which can break DNA strands (w/ exception of sunlight)

  8. Carcinogens • Chemicals • Tobacco smoke, aniline dyes, asbestos, dioxins • Act by damaging DNA molecules

  9. Carcinogens • Virus infection • Ex: Burkitt’s lymphoma, papilloma viruses (HPV) • Viruses carry oncogenes, or regulatory genes that become oncogenes

  10. Carcinogens • Hereditary predisposition • Cancer tends to be more common in some families • The disease itself is often not inherited, but susceptibility to risk factors that create oncogenes are • Some oncogenes, however, are directly inherited (ex: retinoblastoma)

  11. Tumors • Small group of tumor cells = primary growth • Benign: do no spread from site of origin, but can compress and displace surrounding tissue • Malignant: cancerous tumors. Spread throughout body and invade other tissues, eventually destroying them

  12. Malignant tumors • Interfere with normal functioning of tissue where they grow • Cells can break off and spread through the blood and lymph to form secondary growths • Spread of cancer by secondary growths is called metastasis

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