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?? ?? ?? ???. ? ?: ? ? (??????)? ? ?: ? ? ? ? 10 ? ??????? . ?? ?? ??? ??? ??. 1. ?? ???? Basis2. ??? ?? ??3. ??? ?? ? ?? ??? ????. ?? ?? ??? ??? ??. 4.??, ??? ??? ?? ??. ? ???(???), ???(??? ?) ??5.???? ??, ?? ?? ??? ??? ?? ?? ? ex) ?

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    1. ??????? (?????) ????? ??? ??? ? ? ? ?: ? ? ?

    2. ?? ?? ?? ??? ? ?: ? ? (??????) ? ? ?: ? ? ? ? 10 ? ???????

    3. ?? ?? ??? ??? ?? 1. ?? ???? Basis 2. ??? ?? ?? 3. ??? ?? ? ?? ??? ????

    4. ?? ?? ??? ??? ?? 4.??, ??? ??? ?? ??. ? ???(???), ???(??? ?) ?? 5.???? ??, ?? ?? ??? ??? ?? ?? ? ex) ??, ???.

    5. ? 11? ????? 1. ?? ?? 2. ??? ??? ?? 3. ? ?? 4. ???? ??? ?? ?ex) ????? ?? ??, ?? ? ?? ????

    6. ? 11? ????? 5. ????, ?? ?? 6. ???? ?? 7. ?? ? ?, ? ??. ??, ??, ?? ??

    7. ? 11? ????? 1.????? ????? 2.??? 3.??? ?? 4.?? ?? 5.???? ??(function)

    8. ? 11? ????? 6. ??? ? ???? 7. ? ?? 8. ? ? 9. ??? ? ? ?????? 10. ?? ??

    9. ? 2 ? ?????? ?? ?? 1.????? ????? ??? ????? ??? ?? ?? ?????? 1. ????? ??, ???? ?? 2. ??? ??? ??, ????. 3. ?? ????

    10. ? 2 ? ?????? ?? ?? 1)????? ?? ? ?? ?? ?? 2)? ?? ? ? ?? ?? ?? 3)??? ?? ?? ?? 4)??? ?? ?? ?? 5)?? ? ??? ?? ??

    11. ? 2 ? ?????? ?? ?? ?? : ???? ???? ?? ???? ??? ?? ?. ??? ??? ???? ???? ???? ???? ???? ?? ?? ??? ? ??? ?? ??

    12. What is Stroke? Stroke is a type of cardiovascular disease. It affects the arteries leading to and within the brain. When that happens, part of the brain cannot get the blood (and oxygen) it needs, so it starts to die.

    13. What is Stroke? A stroke occurs when a blood vessel that carries oxygen and nutrients to the brain is either blocked by a clot or bursts. ?Ceribral embolism or thrombosis ? ??? ? ?????

    14. Ischemic Stroke The most common type of stroke is caused by a clot or other blockage within an artery leading to the brain. ? Ceribral infarction ? ?????

    15. ? 2 ? ?????? ?? ?? 3. ??? ?? ?????(Hemorheology): ??? ? ????? ??? ?? ?? ?? ???? ?? ?????? ?? ??? ? ??

    16. ? 2 ? ?????? ?? ?? 3. ??? ?? ???? 1) ?? ?? 2) ??? ?? (= Hematocrit HCT) 3) ??? ???(ESR) 4) ??? ?? ?? 5) ??? ??? ??

    17. ? 2 ? ?????? ?? ?? 4. ?? ?? ?? ?? 3 ?? 1. ?? ?? ?? 2. ??? ??? ?? ?? 3. ?? ?? ??? ?? ??.

    18. ? 2 ? ?????? ?? ?? 4. ?? ?? ?? 1. ?? ?? ?? ?? 2.?? ?? ?? ?? 1) ?? ?? ??? 2) ?? ?? ???

    19. Chronic Lymphedema as Vascular Complication of Breast & Pelvic Surgery Current Concepts on Its Management

    20. Acute and/or chronic Local and/or systemic Combined with venous system involvement Vascular Complication of Breast & Pelvic Surgery

    21. Deep vein thrombosis of lower extremity Iliofemoral vein thrombosis - Phlegmasia alba dolens - Phlegmasia cerulea dolens Pulmonary embolism Venous Complication of Pelvic Surgery

    22. ? 2 ? ?????? ?? ?? ?????? thrombocytopenia ? ?? ??? ?? ?? 1?? 15?~60?? ? ?? 1?? ??? ??? 10?? ??? ?? ? ?? ?? ? ??? ?..

    23. ? 2 ? ?????? ?? ?? ??????, thrombocytosis ??? ?? ?? ??? ?? ??. ?? ??? ? ??? ?? ??? ???? ??? ?? ?? ?? ??? ????? ??, ?? ?, ????? ?? ?? ??? ??? ?? ??, ??? ??? ? ??.

    24. What is the Platelet ?

    25. Platelet Adhesion

    26. Platelet Aggregation

    27. ? 2 ? ?????? ?? ?? ???? ?? ?? ????? ??? ??? ?? ????? ??? ?? ?? ????? ??? ?? ??? ?? ?????? ???? ??

    28. Normal Endothelium These include effects on platelets, blood coagulation, and fibrinolysis..

    29. ? 2 ? ?????? ?? ?? ??? ? ???? ?? ????? ? ? ????

    30. ? 2 ? ?????? ?? ?? ?? ?? ? ????? ??? ?? ??. ?? ??? ?? ? ????? ??? ??. ?????(??) ? ??? ?? ?? ??.

    31. Scanning Electron micrograph of the thrombus …in the coronary artery section

    32. Photomicrograph of the arterial infarction

    33. Efficacy of Aspirin Inhibition of platelet activation Risk reduction of stroke

    34. ? 2 ? ?????? ?? ?? ?? ?? ? TC(Total Cholesterol), TG(Triglyceride ), LDL (Low Density Lipoprotein), VLDL(Very Low Density Lipoprotein), HDL (High Density Lipoprotein) ?.. ? ??????, ???? ??? ????. ????? ? ??? ? ? ??????

    35. ? 2 ? ?????? ?? ?? ????? ? ? ???, ????, ??? ??? ?? ?? ?? ???? ????? ? ???? ?? ? ?? ?? ?? ??? ??

    36. ? 11? ????? ?3? ?????? ?? ??

    37. ?????? ?? ??(??) ?? R&D Value Chains

    38. ?? Drug Targets

    39. Post - Genomics

    40. Too many targets?: >5000-10,000 targets Organic chemists have a lot of things to do

    41. Post Genomics Drug Discovery

    42. Lead Generation

    43. New Approach in Lead Generation

    44. Gene Family (?)

    45. Thank you for your attention !!

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