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Inexpensive and Accessible Thermal Imaging for the Detection of Cancer

Inexpensive and Accessible Thermal Imaging for the Detection of Cancer. INFRANOSTICS. Angela Fan Ben Wang Mark Bucklin Nancy Diao Olufunke Laseinde. Methods Used to Screen and Monitor for Cancer. A Problem and a Solution. A Device That Will:. Current Methods.

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Inexpensive and Accessible Thermal Imaging for the Detection of Cancer

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  1. Inexpensive and Accessible Thermal Imaging for the Detection of Cancer INFRANOSTICS Angela Fan Ben Wang Mark Bucklin Nancy Diao OlufunkeLaseinde

  2. Methods Used to Screen and Monitor for Cancer A Problem and a Solution • A Device That Will: • Current Methods • Measure Skin-Surface Temperature • Expensive • Report Topographic Location • Uncomfortable • Be Inexpensive • Inconvenient • Software That Will: • Rely on Presence of Tumor not Growth of Tumor • Map and Record Spatial Temperature Fluctuations • Recognize Patterns of Carcinoma Development

  3. Common Detecting Cancer: Current Methods • Mammography • Self Exam • Ultrasound • Less Common • MRI • PET/CT • Thermography From top left, clockwise: Mammogram (Harvey), Breast Self Exam, Ultrasound of the breast (Tiefenbacher), MRI of the breast with T1 contrast and fat reduction (Harvery), Combined PET and CT (Lavayssiere), Breast Thermogram (http://www.aathermography.com)

  4. CMOS Focal Plane Array Cameras Thermography • ~10 μm IR radiation at 36º C • FDA Approved for Screening Alongside Mammograms • Particularly good at screening for • Breast Cancer • Pain • Neurological Disorders Top to Bottom: Angiogenesis (http://www.gene.com/gene/research/focusareas/oncology/angiogenesis.html), Breast Thermogram (http://www.thermogramcenter.com/Images.htm)

  5. Similar Devices Handheld Optical Scanner Thermal Imaging Camera Single-Sensor Thermography System • Near Infrared Absorbance • Drexel/Upenn • In Clinical Trials Left: Material from Drexel/Upenn device by Chance, B (http://www.biomed.drexel.edu/new04/Content/ProgressReport/fnir_breastcancer.pdf) , Center:Nec TS9100 Thermal Imaging Camera (www.metrum.co.uk) , Thermal Body Scan (http://thermalbodyscan.com/DITI.aspx). Right: Se Jin Yoon, et. Al. A Study of Thermographic Diagnosis System and Imaging Algorithm by Distributed Thermal Data using Single Infrared Sensor. Conf Proc IEEE Eng Med Biol Soc. 2007;2007:3319-22.

  6. Design Specifications/Constraints Versatile -Comfortable and Adaptable Power -Enough power to run a complete body scan Design Specifications/ Constraints Spatially Accurate -Develop Anatomically Relevant Temperature Map Reliable -At least 95% accuracy -Detect temperature changes of ~0.1˚F Software -User Friendly GUI -Pattern Recognition Accessible/Inexpensive -Lightweight & Handheld -Home -Family Physician, -Humanitarian

  7. Components and Related Products Position Tracking Temperature Measurement Accelerometer Gyro Thermopile Optical Sensor Thermistor Optical Sensor

  8. Design Concept #1 Handheld Device • Thermopiles • Optoelectronic Sensors • Gyro/Accelerometer • IR Tracker CPU • Process position • Display Coverage • Store Temperature • Give Directions • Diagnose via Pattern Recognition User Designed with help from: http://gfx-3d-model.blogspot.com/2008/06/laptop-01.htmlhttp://www.linkwitzlab.com/Pluto/w-asp-pcb.jpg

  9. Design Concept #2 • Advantages • Form-fitting, stationary devices allows the surveyed area to be easily mapped • User will be familiar with and the device form • Material will be comfortable. • Disadvantages • Needs to be made for a variety of breast sizes. Designed with help from: http://gfx-3d-model.blogspot.com/2008/06/laptop-01.htmlhttp://www.linkwitzlab.com/Pluto/w-asp-pcb.jpg

  10. Design Concept #3 • Advantages • No complex tracking needed since device would be stationary • Flexible material is suitable for a range of breast sizes • Disadvantages • May be large, and unwieldy • May be uncomfortable

  11. Questions?

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