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Synaptic transmission

Synaptic transmission. Synaptic currents drive spike generation. Summation. Inhibitory synapses. Modeling synaptic inputs. spike input, u(t). pre-. ?. conductance change, g ( t ). post-. “alpha function”. Modeling synaptic inputs. (1) spike input, u(t). pre-.

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Synaptic transmission

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  1. Synaptic transmission

  2. Synaptic currents drive spike generation

  3. Summation

  4. Inhibitory synapses

  5. Modeling synaptic inputs spike input, u(t) pre- ? conductance change, g(t) post- “alpha function”

  6. Modeling synaptic inputs (1) spike input, u(t) pre- (2) low-pass filter, z(t) (3) low-pass filter, g(t) post- “alpha function”

  7. Modeling synaptic inputs g(t) = postsynaptic conductance change (1) spike input, u(t) pre- (2) low-pass filter, z(t) (3) low-pass filter, g(t) post- “alpha function”

  8. Postsynaptic voltage update equation

  9. Postsynaptic voltage update equation pre- ionic currents (e.g., Hodgkin-Huxley) post-

  10. Postsynaptic voltage update equation pre- ionic currents (e.g., Hodgkin-Huxley) post- synaptic currents

  11. Reversal potential

  12. Simple Networks / Reflexes

  13. Flexor/crossed-extensor reflex

  14. Central pattern generation central pattern generator (CPG) -- a neural circuit capable of producing repetitive activity in the absence of any sensory input

  15. Central pattern generation

  16. Reciprocal Inhibition

  17. Post-Inhibitory Rebound

  18. Lobster Gastric Mill Networks

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