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1.900 new children affected each day by AIDS , that is 1 child every 20 seconds

dedicated to Global solidarity. UNITAID sets up programs for. HIV / AIDS. malaria. tuberculosis. 1.900 new children affected each day by AIDS , that is 1 child every 20 seconds. 20% deaths among children in Africa due to malaria , a disease which can be cured….

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1.900 new children affected each day by AIDS , that is 1 child every 20 seconds

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  1. dedicated to Global solidarity UNITAID sets up programs for HIV / AIDS malaria tuberculosis 1.900 new children affected each day by AIDS, that is 1 child every 20 seconds 20% deaths among children in Africa due to malaria, a disease which can be cured… Near 2 billion people affected by tuberculosis, that is one third of the world population

  2. A Global State of Emergency… • Medicines are in the North, patients in the South • The less developed countries represent: • 84% of the world population • less than11% of the global health expenditure • more than 93% of the global disease burden

  3. 2.1 million HIV positive children in the world • 660,000 children need ARV Only 40,000 benefit from it • Drug resistance is increasing • Only 8% of pregnant women get ARV to prevent transmission of the disease to their baby

  4. 1st cause of child mortality for a disease that can be cured • The disease burden is growing • ACTs are the most efficient treatment • against growing drug resistances • (efficient for 95% cases)

  5. 2 million people die from tuberculosis each year • 1st cause of mortality for people with Aids • Drug resistance is growing • Multi drug resistant treatments are extremely expensive (4.000 $/year)

  6. Official signature of the five founder countries when UNITAID was launched, on 19 September 2006, United Nations, New York

  7. 27 donor countries already joined UNITAID Guinea has just joined on 30th August 2007

  8. Countries that implemented the air tickets levy • Tax already in place or now been implemented: • France • Chile • Norway (tax on CO2 from airplanes) • Côte d’Ivoire • Congo • Guinea Conakry • South Korea • Madagascar • Mauritius • Namibia • Niger Countries which have committed to implement the tax: Benin, Burkina Faso, Cameroon, Gabon, Liberia, Mali, Morocco, Central African Republic, Senegal,Sao Tome & Principe, Togo

  9. More than 80% of UNITAID revenue is based on the air ticket levy

  10. Impact of the air tickets levy: an example Antimalarial treatment for 2 children ex: flight Paris - Berlin 1 HIV-positive child under treatment for 1 year ex: flight Paris - Dakar An aircraft with 300 passengers on board leaving from Paris will cover the treatment for 1 person with multi drug resistant tuberculosis, which is very expensive (approx. 4.000 $) Furthermore… no economic impact on air traffic

  11. UNITAID objectives 1/ Improve access to treatment for HIV/AIDS, TB, malaria in developing countries 2/ Get lower prices for quality drugs and diagnostics 3/ Speed up products availability • Predictable long-term funding • A budget over $ 300 million in 2007, 90% being already committed • Price reductions as a result of larger volumes (pool procurement) • 85% of funds for the poorest countries • A small secretariat hosted by WHO: no bureaucracy

  12. UNITAID added value UNITAID use of funds allows to: 1/ have manufactured drugs better adapted to patient needs (fix dose combinations) 2/ reduce prices: more drugs available for the same budget 3/ contribute to a better quality (pre qualification of drugs, incentive for manufacturers to invest) 4/ rapidly deliver drugs in the countries in need

  13. UNITAID uses a wide range of tools to help reduce prices and accelerate availability of drugs COST plus pricing Predictable funding Pool procurement Volume price negotiation Market dynamics forecast Information sharing Encouraging/attracting new manufacturers Encouraging market competition Prequalification Encouraging technology sharing Supporting local registration Partnership pricing Loweringbarriers to entry on market Reference price / price ceiling

  14. A unique partnership model UNITAID works together with well-recognized partners :

  15. In the last months, UNITAID has committed to funding projects against the three diseases…

  16. Ongoing UNITAID programs HIV / AIDS I/ Pediatric ARV: Have 100,000 new HIV-positive children under adapted ARV treatments in 2007 (today only 40,000 are covered when 660,000 need it) in 40 countries. II/ 2nd line ARV: reduce prices for 7 products and provide treatments for 60,000 new patients in 27 countries in 2007. III/ Prevention of mother to child transmission: improve the care, reduce diagnostic prices, have 1.2 million pregnant women tested and 340,000 under ARV treatment in 8 countries in 2007-2008. Partner: the Clinton Foundation Partners: WHO and UNICEF

  17. 53 recipient countries from UNITAID funds against HIV / AIDS SEARO India Thailand WPRO Cambodia China Lao Papua New Guinea Vietnam AMRO Dominican Rep. Guyana Haiti Jamaica OECS (Anguilla, Dominica, St Lucia, Antigua & Barbuda, Grenada, St Christopher & Nevis, British Virgin Islands, Montserrat, St Vincent & Grenadines) EURO Moldova Serbia EMRO Djibouti Morocco Tunisia AFRO Angola Benin Botswana Burkina Faso Burundi Cameroon Chad DRC Cote d'Ivoire Ethiopia Ghana Guinea Kenya Lesotho Liberia Malawi Mali Mozambique Namibia Nigeria Rwanda Senegal South Africa Swaziland Tanzania Togo Uganda Zambia Zimbabwe

  18. Ongoing UNITAID programs Malaria Partners: The Global Fund and UNICEF I/ ACT scale up: Scale up ACT treatments in eleven countries, until 2010, for 55 million treatments, in order to have an impact on prices, give an incentive to manufacturers, avoid stock out in countries. II/ ACT program in Liberia and Burundi: Provide nearly 1.3 million treatments in these two countries that had no coverage for 2007, before other donors stepped in. Partners: WHO and UNICEF

  19. 22 recipient countries from UNITAID funds against malaria AFRO Burundi Cote d'Ivoire Eritrea Ethiopia Gambia Ghana Guinea Guinea Bissau Liberia Madagascar Mali Mauritania Mozambique Namibia Somalia Zambia EMRO Djibouti Sudan SEARO Bangladesh Indonesia WPRO Cambodia China

  20. Ongoing UNITAID programs Tuberculosis Partner: The Global Drug Facility I/ 1st line TB : Support the transitional provision of 740,000 treatments in 2007-2008 for 18 countries and establish a strategic rotating stockpile. II/ Pediatric TB: provide treatments adapted to children in order to treat 150,000 children by the end of 2007. III/ Multi drug resistant TB : Support the purchase of 4,700 treatments in 2007 for 17 low income and lower middle income countries, with a view to decreasing prices. Partners: WHO and UNICEF Partners: The Global Drug Facility and the Global Fund

  21. 58 recipient countries from UNITAID funds against tuberculosis AFRO Benin Burkina Faso Cape Verde Cameroon Congo Brazzaville DRC Cote d'Ivoire The Gambia Guinea Kenya Lesotho Madagascar Malawi Mali Mauritania Mozambique Niger Nigeria Rwanda Somalia Tanzania Togo Uganda Zambia SEARO Bangladesh Bhutan India Indonesia Myanmar Nepal Sri Lanka Timor-Leste EURO Azerbaijan Bosnia-Herzegovina Belarus Bulgaria Georgia Kyrgyzstan Kazakhstan Moldova Tajikistan Uzbekistan EMRO Afghanistan Djibouti Egypt Iraq Lebanon Pakistan Syrian Arab Rep. Yemen WPRO Cambodia Lao Philippines Vietnam AMRO Dominican Rep. Guatemala Haiti

  22. Facing a global state of emergency, UNITAID contributes to bring solutions In less than a year, UNITAID has already achieved major results…

  23. 1/ First significant price reductions 30 November 2006 on antiretroviral for HIV positive children (with the Clinton foundation) 8 May 2007 on second-line antiretroviral (with the Clinton foundation)

  24. UNITAID first results "My long experience in public policy taught me that even those who don't like taxes are not reluctant to pay a contribution for a good cause. Thanks to UNITAID, we succeeded to lower the annual cost of a treatment for a child with AIDS from 196 $ to 60 $. Each citizen who gets into an plane and pays its contribution should reflects on that : with the same amount of money, we save three time more children.." President Bill Clinton Le Monde – 25th July 2007

  25. 2/ More user-friendly drugs • With UNITAID funding, new treatments put on the market against HIV/AIDS are more adapted : • Doses well adapted to children corpulence • Drugs to be taken in the form of tablets (fix dose combination) : • 1 tablet replaces several doses daily • Heat stable drugs : no refrigeration needed anymore • No need to dilute them in water (problem of access to drinkable water • in some countries).

  26. Daily treatment for a patient

  27. 3/ The first drugs already in the field… against HIV/AIDS Number of children under treatment (31st May 2007) (000’s) Pediatric ARV program with the Clinton foundation 28,229 new children 40,758 children already under treatment TOTAL Source: Clinton foundation

  28. Results obtained: Impact for a patient Jennifer On admission Atter 3 months After 5 months Pediatric ARV program with the Clinton foundation Source: Partners In Health / Clinton foundation

  29. Against malaria Arrival on 12th June 2007 of 670,000 ACTdoses in Liberia that will help to prevent the death of 6,800 children per year (partners: UNICEF / WHO)

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