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COUNTERCURRENT MULTIPLICATION

COUNTERCURRENT MULTIPLICATION. countercurrent multiplication refers to the ability of the kidney to increase the osmolality of the interstitium from the normal tissue value of 300 mosm/kg up to 1200-1400 mosm/kg this is necessary to allow the kidney to be able to concentrate the urine.

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COUNTERCURRENT MULTIPLICATION

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  1. COUNTERCURRENT MULTIPLICATION • countercurrent multiplication refers to the ability of the kidney to increase the osmolality of the interstitium from the normal tissue value of 300 mosm/kg up to 1200-1400 mosm/kg • this is necessary to allow the kidney to be able to concentrate the urine

  2. COUNTERCURRENT MULTIPLICATION TIME 0 300 300 300 300 300 300 300

  3. COUNTERCURRENT MULTIPLICATION TIME 1 300 300 300 300 NaCl 500 100 200 mosm 300

  4. COUNTERCURRENT MULTIPLICATION TIME 2 300 300 NaCl 300 100 200 mosm NaCl 500 300 200 mosm 500

  5. COUNTERCURRENT MULTIPLICATION TIME 3 300 100 NaCl 500 300 200 mosm NaCl 700 500 200 mosm 500

  6. COUNTERCURRENT MULTIPLICATION TIME 4 NaCl 300 100 200 mosm NaCl 500 300 200 mosm NaCl 700 500 200 mosm 700

  7. COUNTERCURRENT MULTIPLICATION TIME 5 500 300 700 500 900 700 900

  8. COUNTERCURRENT MULTIPLICATION TIME 6 700 500 900 700 1100 900 1100

  9. COUNTERCURRENT MULTIPLICATION TIME 7 700 500 900 700 1100 900 1100

  10. COUNTERCURRENT MULTIPLICATION 300 300 300 300 300 100 300 300 500 100 300 500 300 300 500 900 700 500 300 500 700 900 1100 700 500 900 700 500 700 900

  11. COUNTERCURRENT MULTIPLICATIONTHE ROLE OF UREA CD Water Water urea Loop

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