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Digital Pathology Empowering pathologists

Digital Pathology Empowering pathologists. Bob van Gemen. October, 2008. Founded in 1891 Headquarters: Amsterdam, The Netherlands One of the largest global diversified industrial company with sales in 2007 of EUR 26,793 million Multinational workforce of 123,800 employees (January 2008)

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Digital Pathology Empowering pathologists

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  1. Digital PathologyEmpowering pathologists Bob van Gemen October, 2008

  2. Founded in 1891 Headquarters: Amsterdam, The Netherlands One of the largest global diversified industrial company with sales in 2007 of EUR 26,793 million Multinational workforce of 123,800 employees (January 2008) Manufacturing sites in 28 countries, sales outlets in 150 countries R&D expenditures EUR 1,619 mln (2006) Royal Philips Electronics

  3. Incubator Incubator Incubator Since 1 Jan 2006, there are 3 Incubators within Philips to further New Business Development Healthcare Lifestyle Technology 2

  4. Philips Research HI Sector Road Maps Strategic Focus Healthcare Incubator FutureGrowth Market Stage Emerging Growth PD Roadmap, PD Incubation& Contract Research Established Current Emerging Potential Future Philips capabilities

  5. PH, CLS, L Research New BU in IEB Other Philips Spin-together Outside Incubation Process at Philips 1. Pre- 2. Seed 3. Alpha 4. Beta 5. Scaling seed Create value for Philips by1. finding superior venture opportunities and 2. making them work

  6. Healthcare Incubator scope & selection criteria Scope • Involvement of medical profession • Medically validated solution required (e.g. FDA approval) Selection Criteria • Large market potential • Strong value proposition • Capable team • Strong IPR position • Link to Philips strategy • Venture can be run independent of Philips • There are synergies with Philips capabilities or assets

  7. Challenges in Pathology Baby Boomers, age distribution (USA) Pathology graduates decreasing Lack of consensus More stains 6% AAGR 70% accuracy among average pathologists 16.8% AAGR

  8. Pathology oncology care cycle Radiology Clinic initiatediagnostic procedure Biopsy Imagecreation Radiologist Pathologist Image-baseddiagnostics Written report PACS, RIS Clinic: treatment advice

  9. Digital Pathology: empowering the pathologist Scanner Path. Information System CADCDS Expertpathologists PathologyLab PACS Radiologist Oncologist MedicalSpecialist EPR

  10. Value proposition Digital Pathology in Cancer Dx Quantification single Quantification multiple Morphology based IHC IHC CAD/CDS Value

  11. Data acquisition: importance of data processing • Even though a slide is “small”, imaging of biological specimens requires 100’s of millions of pixels. • Philips strength from Imaging in Radiology (e.g. whole body CT scan) • Better handling and viewing due to expertise from Radiology PACS

  12. Interesting possible solutions 4 1 2 3 QA Productivity Patient safety Advisor • Clinical relevant solutions • follows clinical needs • development with clinical sites • scanner independent Pathology PACS (viewer & storage) • Technology basis • hardware and software • open system • enables clinical solutions Digital scanner

  13. How to optimize the anatomic pathology workflow? Slide production 1. Single batch • Is a more continuous process more efficient? • What is the optimal workflow for scanning slides? • Model with output in terms of: • turn-around-times • lab equipment • human resources Diagnosis 2. Small batches 3. Continuous

  14. Development in collaboration with: Pathology departments in 3-4 of the top 10 cancer hospitals in USA University Hospitals and Med Schools in USA Same in Europe Companies with synergistic technology

  15. Digital Pathology delivers benefits for Oncology Care Cycles Short term Long term

  16. Pathology PACS screen shot: patient list

  17. Pathology PACS screen shot: image viewer

  18. Pathology PACS screen shot: multiple images

  19. Pathology PACS screen shot: 3D rebuild

  20. Thank you

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