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Polysomes and polypeptide elongation

Polysomes and polypeptide elongation. Sun Hwa Dong. Polysomes (=Polyribosomes). Group of ribosomes bound to a mRNA Read one strand of mRNA simultaneously To translate, each ribosome follows repeated steps After each repetition, one amino acid is added to elongating polypeptide.

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Polysomes and polypeptide elongation

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  1. Polysomes and polypeptide elongation Sun Hwa Dong

  2. Polysomes (=Polyribosomes) • Group of ribosomes bound to a mRNA • Read one strand of mRNA simultaneously • To translate, each ribosome follows repeated steps • After each repetition, one amino acid is added to elongating polypeptide

  3. Polypeptide Elongation • A tRNA – amino acid approaches the ribosome and binds at A site. • 2 tRNAs can be at a ribosome at one time; the anticodons are paired to codons • Peptide bond formation attaches the peptide chain to the newly arrived amino acid • The ribosomes moves forward; “empty” tRNA exists from the E site; the next amino acid-tRNA complex is approaching the ribosome

  4. Vocabulary • Polysomes • mRNA, tRNA • Amino acid • Codon, anticodon • Polypeptide elongation

  5. Bibliography • Study guide pg 64 • http://classes.midlandstech.edu/carterp/Courses/bio101/chap14/chap14.htm • http://www.emc.maricopa.edu/faculty/farabee/biobk/biobookprotsyn.html

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