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PART IV

This summary highlights the benefits of employing a detailed business case with a net present value calculation for APS-supported processes in the supply chain. The resulting benefits include cost reduction, enhanced flexibility and integration, and improved decision-making transparency.

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PART IV

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  1. PART IV ARCHITECTURE OF SELECTED APS

  2. SUMMARY of Last Lecture For all projects a detailed business case with a net present value calculation on the entire supply chain was employed in advance. The resulting, here represented, benefits evidently indicate a two-digit million Euro amount. For the monitoring of these benefits a continuous recalculation took place and has confirmed the assumed benefits. Simultaneously, a performance management system was established along the new APS-supported processes. Summarizing, all these benefits lead to a stable and durable enhancement of the margin contribution along the complete downstream supply chain and a competitive advantage of the company in the relevant market. At the same time especially the high grade of flexibility and integration of the available planning, optimization, scheduling and management systems. Smaller raw material costs through an enhanced crude oil selection to fulfill the market demand,

  3. Cont’d… • Reduction of production costs through a decrease of variable production costs, • Reduction on working capital costs in inventories of crude oil and finished products, • Enforced utilization of margin upgrade potentials through increased transparency, • Persistent realization of the MP (optimization) results through quota formation and quota management, as well as its coordination over different responsibility levels, • Transparency and as a result acceptance of decisions. Future main emphases will be identified and pursued further in the field of demand forecasting, short-term optimization, scheduling and management of the supply chain under the criteria of revenue management.

  4. Supply Chain Description and Typology Requirements for Planning On the base of these supply chain characteristics the main challenges for a planning, optimization and scheduling system are as following. Due to the long lead times for the refinery’s crude oil supply, the decision of crude oil purchase, e.g., which kind of crude oil sort in which quantity, at what purchase price and at what time—which is the most important financial decision—is the major focus. Therefore high forecast accuracy for a future customer demand per single product is fundamental.

  5. Requirements for Planning • On the base of these supply chain characteristics the main challenges for a planning, optimization and scheduling system are as following. Due to the long lead times for the refinery’s crude oil supply, the decision of crude oil purchase, e.g., which kind of crude oil sort in which quantity, at what purchase price and at what time—which is the most important financial decision—is the major focus. Therefore high forecast accuracy for a future customer demand per single product is fundamental. • After this decision about the crude oil supply the degrees of freedom for changes are limited, e.g., the ordered crude oil transported by ship cannot be switched or sold easily, at most with financial losses.

  6. Description of the Ideal Planning System • For all decisions mentioned in Sect. an integrated planning system, which generates solutions in an optimal way on various questions concerning the whole supply chain at different points in time, is required. Figure describes the entire planning system architecture. In this section, every single planning module of the developed planning system will be described. The corresponding software modules are then added in Sect. Every planning cycle starts with the Supply & Demand Planning (S&DP). The base for these forecasting processes are estimations from the market analysis department. This department is delivering expectations on market demands per country, on demanded product qualities and especially on expected price levels (quotations) for crude oil and finished products. Based on this information, planned sales numbers for the individual sales markets will be collected from every sales channel, e.g., estimated sales quantities and sales prices per region for diesel.

  7. Cont’d…. Parallel to this the evaluation of quantities, available on external supply sources, and their corresponding prices (purchase costs) for different crude oil sorts, semi finished products and finished products takes place, e.g., the available quantities and the purchase costs of the finished product diesel at an external refinery. To leave freedom for optimization the potential sales quantities as well as the available purchase quantities are planned as minimal and maximal bounds on sales/purchase. Additionally, availabilities of finished products on external sources (as input for a “make-or-buy” decision) and their purchasing costs have to be estimated.

  8. Introduction of Supply and Demand Manager • Introduction of a standardized and integrated planning system in all countries for the S&DP, including the features: – Automated collection of all relevant MP data, uniform for all countries and sales channels – Creation of a harmonized data base for all planning data • Simultaneous forecasting of quantities and prices/costs (concerning customer demand, external purchasing and crude oil supply) • Enabling process transparency & -monitoring (alerting) • Increase of forecast accuracy by introduction of an APS-based Demand Planning module • Higher transparency of the MP results by implementing a web-based front end reporting. Thus an APS module was looked for, simultaneously supporting both the existing MP solution and the above mentioned aims. After an extensive blueprinting and a following proof of concept SAP APO was chosen as the software module for putting the S&DP processes into practice.

  9. Cont’d… In order to sufficiently represent the existing business model, six forecast dimensions as well as nine related attributes had to be introduced and stored. In the following examples (see Fig. 24.4) we will concentrate on the three dimensions • • Sales channel, comprising product (groups) like gasoline, diesel, heating and aviation fuel, which are assigned to business units like “Retail” (responsible for filling stations) or “Commercial” (responsible for heating, aviation, etc.) • • Geography, comprising customer (groups), regions, countries and clusters (e.g., a set of countries) • • Time (e.g., days, months). The planning process of the S&DM usually starts with forecasting the future (basic) prices of crude oil (Brent), the finished products’ quotations or reference quotations for local markets as well as the exchange rates for the relevant countries. For markets, which are not directly following the global prices, a local finished product price scenario and local purchase prices (prices which the company could buy for from external refineries) have to be estimated.

  10. Implementation of Product Supply Scheduling • The second project, the “Implementation of the Product Supply Scheduling”, had the following objectives: • Introduction of a standardized and integrated Allocation Planning and Quota Management system in all countries to close the gap between MP and the operational fulfillment of the customer demand, including the features – Hierarchical disaggregation of the MP results as part of the Allocation Planning – Possibility to provide sales & supply patterns for all quotas – On-line interface for monthly quota check between SAP APO and SAP R/3 SD • Calculation and estimation on the progress of quota consumption during the month for all responsibility levels (refinery production, depot supply & management, sales, purchase) and aggregation levels • On-line volume (quota) availability check by creating a customer sales order • Handling of quota changes via cockpit • Monitoring, alerting and web-based presentation of unexpected deviations in quota consumption • Setting up a performance management to measure the planning quality, the scheduling efficiency (sales pattern accuracy) and Quota Management efficiency for all responsibility levels.

  11. Cont’d…. • The MP optimization results, which are stored in the SAP APO BW, are the starting point for the Allocation Planning (AP). They are uploaded into a separate planning sphere for both AP and the later Quota Management. Since the MP results are only available in an aggregate form, e.g., over all customers of a business unit, it is up to AP to disaggregate them again according to the different dimensions of the forecasting hierarchy (see Fig. 24.6). This is a crucial task if the scarce capacities of MP led to (aggregate) shortages of the original (detailed) forecasts (see Sect. 9.4.4). AP supports this allocation by providing rules for the automatic disaggregation along inter sections of the sales channel/geography dimensions and along the time dimension.

  12. Cont’d…. • To create this separate sphere the structure of the optimization result has to be extended for the missing attribute combinations, e.g., from business units/clusters to products/customers. Next the allocation of the available quantity per product/ customer along the sales channel/geography dimensions takes place as following: at first the minimally demanded quantity (i.e., the detailed minimum sales quantity estimated in S&DP, the so-called “contract quantity”) will be replenished on the lowest level of the hierarchy. Thereafter the residuary quantity, which is the quantity the optimization model has determined between the aggregate minimum and maximum boundaries of MP, will be allocated to the customer with the highest sales price. The quantity on that customer is replenished until its maximum is reached (i.e., the detailed maximum sales quantity forecast in S&DP). After that the customer with the second highest price gets the quantity up to its maximum and this sequence goes further until all MP quantities are allocated.

  13. Lecture 30 SCM in a Pharmaceutical Company CHAP 25 • Tanguy Caillet

  14. LAYOUT • Introduction • Case Description • Objectives of the Project • The TO-BE Vision • Planning Processes • Results and Lessons Learned

  15. Introduction Competitive advantage in the pharmaceutical industry is driven by first class research and development and by optimised supply chain operations. Harmonised SCM processes, systems and organisations will lead to reduced inventories, increased capacity utilization, reduced order lead time, less obsolescences and lower IT system maintenance costs. Critical decisions can be made faster resulting in an improved customer service level. Based on common, standardised data, error rates are reduced and most importantly, full FDA CFR 21 part 11 and GMP compliance can be guaranteed and sustained.

  16. Case Description Topology of the Pharmaceuticals Supply Chain The supply chain consists basically of three main levels: chemical plants, pharmaceutical plants and marketing affiliates. The chemical plants deliver the active ingredient (AI). The production of the AI within the chemical plants has not been tackled within the project as the manufacturing process differs significantly from the one of the pharmaceutical plants. The chemical plants, either part of the same company or third party suppliers, are treated as suppliers. Material requirements are planned by the Supply Network Planning module for the entire planning horizon (24 months).

  17. SUPPLY CHAIN, SYSTEMS AND PROCESSES

  18. THE AS-IS SITUATION At the start of the project, a very heterogeneous environment, grown over the last decades, was in place. The following list highlights some key aspects of the company’s as-is situation: • Four SAP R/3 systems (two running R/3 PP, two running R/3 PP-PI), one BPCS system,2 one R/2 system were used. Data integration between the systems was low, data structures not harmonised. The same product existed with several material numbers in different systems. Information sharing as well as synergies out of a common system were not achievable. • No central supply chain network planning system was available, resulting in basically no central visibility of the supply chain constraints and problems. • Production Planning and Detailed Scheduling of the manufacturing processes were performed in various stand-alone systems and spreadsheets, interfaced with local ERP systems. This resulted in massive manual planning effort and sub optimal capacity utilization. • There was no central statistical forecasting system in the as-is environment. • KPI measurements were not consistently defined and did not support common targets.

  19. Objectives of the Project The objectives of the project were the creation of 1. a to-be supply chain vision with a clear objective to implement best practice processes enabling the future growth of the company 2. a to-be system landscape supporting the to-be supply chain vision and following a global strategy.

  20. The To – Be Vision To achieve the targeted goals of harmonised processes, systems, data and organizational units, the heterogeneous as-is environment was reengineered, and a streamlined and integrated to-be environment had to be designed. In the to-be environment the six ERP systems are integrated into one central SAP R/3 system. Based on the central ERP system for the entire company one central APS will be setup, representing the entire supply chain. The list below summaries the major features of the to-be environment: • Changing the entire organization from local, function-oriented thinking to acommon European company, sharing the same targets and commitment in true collaboration between the business functions and the supporting IT function • Building of an European team to support that challenging vision on both, IT and business side • Basing the project funding on expected benefits, proven by a business case performed before the implementation started • Buy-in of all involved stakeholders right from the beginning to propagate the new vision and to support its implementation

  21. SIMPLIFIED PROCESS MAP

  22. SIMPLIFIED SYSTEM LANDSCAPE

  23. Planning Processes The planning processes introduced in Fig. 25.2 were mapped to the following ERP and APS modules The implementation of SAP APO PP/DS and SAP APO SNP, being the main enablers of the supply chain benefits envisioned in the initial phase of the project, are described in the next two sections.

  24. PRODUCTION PLANNING AND DETAILEDCHEDULING: APO PP/DS/DS • The Planning Model. As mentioned before, the product range of the company is very heterogeneous, including solids, liquids & creams, steriles, patches, biotech and medical devices. This variety requires APO PP/DS to support a broad range of constraints and planning scenarios: • • Finite capacity of manufacturing resources • • Availability of labor force • • Prohibition to operate defined resources in parallel • • Priorities for a production or procurement alternative • • Availability of critical components • • Maximum holding time of products before next processing step • • Minimum waiting time between manufacturing steps • • Various lot-sizing rules.

  25. Cont’d…. The production plan is generated automatically by APO PP/DS. Based on the production plan a sequenced schedule is computed. This requires the optimization of the following parameters: • • Reduction of machine set-ups by producing products of equal set-up groups in a sequence • • Production sequence ordered by increasing compound concentrations to avoid intermediate cleanings • • Production sequence grouped by product and ordered by increasing order quantity, such that in case of quantity deviations of the packed bulk batch, the yield is on the biggest order (the relative deviation will be the smallest for the biggest order) • • In case of bulk material with an intermediate storage in a holding tank, the holding tank has to be emptied as soon as possible, requiring to group products consuming the same bulk material together.

  26. Process Integration • The production planning and detailed scheduling process transforms demand into feasible production proposals and feeds back information about the actual production execution into the planning processes. Out of the master plan generated by the Supply Network Planning module (SNP) planned orders (fixed and unfixed ones) are created to be further processed by PP/DS. As a first step in the overall planning cycle (see Fig. 25.5), the SNP planned orders are manually converted into PP/DS planned orders by the planner. Compared to the bucketised SNP orders the PP/DS orders are time continuous, i.e. they have a precise start and end time.3 The PP/DS production orders are planned with respect to critical materials only that may constrain the plan. Uncritical materials not constraining the plan are planned by the MRP process in R/3, based on the PP/DS production plan.

  27. SET-UP OF THE MASTER DATA MODEL As the effort spent on master data for the implementation exceeded 60% of the total project volume, this topic will be discussed in more detail. All relevant master data (see also list below) is mostly already existing in SAP R/3: • • R/3 material master data (D products in APO) • • R/3 resources & capacities (D resources in APO) • • R/3 recipes and bill of materials linked by production versions (D production process models/PPMs in APO) • • Existing in APO only: Set-up matrixes indicating the duration and cost of a transition of one set-up group to another (from one product to another). For the integration of master data from SAP R/3 to APO PP/DS the standard core interface (CIF) was used.

  28. MASTER PLANNING: APO SNP The SAP APO SNP solution was designed to take full advantage of the standard functionalities of the tool, and to prepare the company for the future steps in Master Planning performed by APO SNP on a 24-months horizon • • Global network representing the complete flow of materials from affiliates to distribution centers, the pharmaceutical and the chemical plants • • Integration of critical suppliers, for direct purchasing as well as third party manufacturers with monitoring of their available capacity • • Utilisation of the Vendor Managed Inventory scenario with 20 affiliates • • Weekly release of the forecast from Demand Planning to SNP • • Demand constrained by the supply plan based on the global SNP optimiser run • • Monitoring of the supply network with generation of alerts depending of the planning situation • • Deployment of the available supply at the plants and at distribution centers to the VMI customers • • Transport Load Building to propose an optimised loading of the different transportation modes (truck, air cargo, sea container, parcel) for the VMI customers only.

  29. SNP Planning Process The SNP planning process is based on a weekly planning run of the SNP optimiser for the complete supply chain except the third party manufacturers.4 Based on the weekly release of the forecast from the Demand Planning module at the VMI customers and at the shipping distribution center for non-VMI customers, the optimiser is planning the network while respecting the following constraints: • • Production constraints at the plants • • Due dates of the demand • • Safety stock levels at the VMI customers • • Availability of the critical components like active ingredients from the chemical plants • • Fixed lot size of the formulation batches • • Distribution and transportation lead times.

  30. Results and Lessons Learned Achieved Results The main benefits envisioned in the business case prior to the APS implementation were achieved. These are in detail: • • The visibility and problem solving capabilities of the entire organization improved by the use of a common data basis and a common visualisation tool, allowing better and faster decisions. • • System based finite capacity scheduling and fast simulation capabilities improved the plan stability and resource utilization significantly. • • Collaborative demand planning with the customers allows for a proactive stabilisation of the demand as changes in the demand by the customer are compared with a constrained demand from the previous master planning run and exceptions are generated. • • The master planning run enables the company to better foresee the future capacity issues and plan accordingly future investments.

  31. Cont’d….. • By reducing the order to cash cycle, as well as pushing for more collaboration with the affiliates through a VMI process, the inventory levels were reduced. • • The collaborative concept and the reduction of supply chain steps have increased the overall reliability of the processes. The reduced time to market has lessened the risk of obsolescences which is an important driver to improve the cash flow of a pharmaceutical company. • • By consolidating the system landscape, the IT maintenance costs were reduced significantly. • • Standardization of the master data enables the visibility and interchangeability of • information faster across the supply chain. • • The overall administrative workload for tasks performed previously manually or based on wrong information was reduced significantly. • • Seven local organisations grew together into one European organization.

  32. Summary Without organizational changes and business process reengineering, the risk of implementing the as-is situation within a new tool is real. The to-be vision needs to be propagated by the upper management towards the different organisations of the company to reduce their resistance to change. This has proven mainly true wherever boundaries between the organisations had to be broken down. The KPI measurements should follow the new processes and be revised accordingly. Keeping previous KPIs will not facilitate change as the old way of working is imposed. The planning processes have to be seen and defined in an integrated way. Demand planning—master planning—production planning—materials requirements planning have to be integrated technically and from an organizational point of view. VMI processes based on Collaborative Planning, Forecasting, and Replenishment (CPFR) could only partly be realised. The marketing affiliates, although part of the same company, were granted control of the

  33. Cont’d…. replenishment demand towards the plants. They were accepting the result of the replenishment planning run and/or changing the result according to their needs, allowing manual override of the VMI concept. Therefore, contingencies have to be built up in form of inventory to cover uncertain changes in the affiliate’s requirements, annihilating the benefits of the VMI process. The success in the implementation of a VMI scenario is not determined by the technical integration of different systems, but strikingly driven by the relationship of the partners and their ability to rely on one another. A global master planning run as foreseen and supplied by SAP APO SNP will be implemented gradually only. The change management efforts from the function oriented supply chain organization to a single and integrated European supply chain is estimated as a project risk due to the expected resistance within the organisations. Reactivity of the supply chain will only increase once the master planning can be executed in one integrated step.

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