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ACLS Guidelines 2010 The rules and changes

ACLS Guidelines 2010 The rules and changes. Peter Cameron, MD The Alfred Hospital/Monash University Melbourne, Australia. The New ACLS Guideline. Published online Oct 18 2010 Published in Circulation Nov 2 2010

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ACLS Guidelines 2010 The rules and changes

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  1. ACLS Guidelines 2010The rules and changes Peter Cameron, MD The Alfred Hospital/Monash University Melbourne, Australia

  2. The New ACLS Guideline • Published online Oct 18 2010 • Published in Circulation Nov 2 2010 • Similar endorsements from Australian/NZ/European and International Resuscitation Councils

  3. 1n 1960 Kouwenhoven & Knickerbocker - 14 patients survive arrest with CPR! • 2 years later direct current defibrillator introduced • 1966 first AHA guidelines • 2010 was the 50 anniversary of CPR

  4. Smart People • 356 resuscitation experts • 29 countries • 36 month period • 411 scientific reviews

  5. “the new recommendations do not imply that care using past guidelines is either unsafe or ineffective” • “still insufficient data to demonstrate that any drugs or mechanical CPR devices improve long-term outcome after cardiac arrest”

  6. ACLS 2010 Guideline Review • Basic Life Support (BLS) • Cardiac Arrest • Tachycardias • Bradycardias

  7. BLS

  8. BLS Principles – DRS ABCD • No change to Dangers and Response • S – Send for help • A – open the Airway • B – check Breathing but no need to deliver two rescue breaths • C – perform 30 Compressions for victims who are unresponsive and not breathing normally, followed by 2 breaths • D – attach an AED as soon as it is available

  9. BLS Principles – DRS ABCD • Compressions before 2 initial rescue breaths • “Signs of life” changed to “unresponsive and not breathing normally” • If unwilling / unable to perform rescue breathing, then perform compression only CPR • New focus on maintenance of CPR quality – change rescuers every two minutes • Pulse check downgraded for HCPs – “unreliable indicator of the need for resuscitation”

  10. BLS – Compressions • One or two handed technique for children (Australian Ambulance have adopted two) • Push to a depth of at least 5 cms at a rate of at least 100 / min • Allow full recoil of chest between compressions • 30 Compressions : 2 ventilations for all age groups (1 or 2 rescuer) • Apply AED (if available) – now BLS skill taught as part of CPR programs

  11. BLS – Health Professional (Cont) • CPR Rates: • Single Rescuer: 30 Compressions : 2 ventilations at a rate of > 100 per minute for all age groups (Approx 5 cycles every 2 minutes – <18 seconds/cycle) • Two Rescuer: Adult – 30:2 at rate of 100 per minute • Two Rescuer: Child (0-14) 15:2 at rate of 100 per minute (Approx 10 cycles every 2 minutes) • Pause to allow ventilations (until intubated or LMA insitu)

  12. BLS – Health Professional (Cont) • AED - Apply and follow the prompts • Continue until signs of life – briefly check (?pulse) every two minutes (don’t pause CPR for more than 10 seconds!!) • Change compressor every 2 minutes to avoid fatigue

  13. AED • AED - Single shock strategy • 2 minutes CPR before reanalysis • No need to reprogram energy levels – should follow those programmed by manufacturer for their specific device • Reasonable to continue to utilise older devices until replaced as part of normal life cycle – any resuscitation is better than none

  14. Choking (FBAO)

  15. CPR Changes Emphasise “Push hard, push fast, minimise interruptions; allow full chest recoil, and don’t hyperventilate”

  16. Rationale • Although ventilations are impt part of resuscitation, evidence shows that compressions are the critical element in adult resuscitation. In the A-B-C sequence, compressions are often delayed. • If a pulse is not detected within 10 seconds, do start compressions without further delay.

  17. Compression Depths • Compression depths are: • Adult- at least 2 inches (5cm) • Children- at least 1/3 the depth of the chest (appx 2 inches (5cm) • Infants- at least 1/3 the depth of the chest, approx 1 1/2 inches (4cm)

  18. Airway & Breathing • Cricoid pressure is no longer routinely recommended for use with ventilations • Randomized control trials demonstrated cricoid pressure still allows for aspiration. It is also difficult to train providers to perform the maneuver correctly.

  19. ALS Principles • To provide critical blood flow to the vital organs with high quality chest compressions • Defibrillation as soon as possible provides the best chance of survival in victims with VF or pulseless VT (cf. CPR prior to defib) • Return of spontaneous circulation as rapidly as possible • Intensive care support aimed to achieve the best outcomes

  20. ALS Principles – Key revisions I • High quality chest compressions with minimal interruptions; continuing compressions during defibrillator charging • Single (non-stacked) shocks, but stacked shocks may be considered for HPC witnessed arrest*, during cardiac catheterisation or after cardiac surgery • Precordial thump is de-emphasised • IV or IO drug administration (ETT de-emphasised) *Where a monitor / defibrillator is connected at the time

  21. ALS Principles – Key revisions II • Adrenaline 1mg for VF/VT after the second shock once chest compressions have restarted and then every 3-5 min (alternate blocks of CPR) • Amiodarone 300mg after third shock • Atropine no longer recommended for routine use in asystole or PEA • Less emphasis on early intubation • Capnography to confirm and continually monitor tracheal tube placement, quality of CPR, and to provide early indication of ROSC

  22. Post Resuscitation Care • Recognition that a “post resuscitation care’ protocol may improve survival following ROSC • Avoid hyperoxaemia – oxygen titration to Sa02 94-98% • Primary PCI in appropriate patients with sustained ROSC • Normoglycaemic glucose control (BSL >10 mmol/l should be treated but hypoglycaemia avoided) • Therapeutic hypothermia to include comotose survivors of cardiac arrest of any rhythm

  23. Single Shock Defibrillation Strategy • Single shock strategy continues to be recommended to improve outcome by reducing interruption of chest compressions • Monophasic 360J / Biphasic 200 J (Adult) • Monophasic / Biphasic 4J/kg (Paed) • Exception is health professional witnessed VF/VT. • Salvo of three stacked shocks (Mono 360J / Biphasic 200J; with rhythm checks between shocks) • Followed by CPR and single shock strategy if unsuccessful

  24. PLS Principles – Key revisions I • Recognition that HCPs cannot reliably determine the presence of a pulse in < 10s. • Compress at least 1/3 AP diameter (Approx. 5cms in children and 4cms in infants) • Defibrillation is a single shock of 4J/kg (mono or bi). Staked shocks as per adult • IV or IO drug administration (ETT de-emphasised) • Cuffed tracheal tubes ok for short term

  25. Newborn Resuscitation I • For uncomplicated babies, a delay in cord clamping of at least one minute from delivery is recommended • For term infants, air should be used initially. • Recommended CV ratio remains 3:1 • Very prem infants should be placed in / under a polyethylene bag or sheet to the neck

  26. Newborn Resuscitation II • Adrenaline IV dose 20-30 mcg/kg. (ET would require at least 50-100 mcg/kg to achieve a similar effect to 10 mcg/kg IV) • Infants with evolving moderate – severe hypoxic – ischaemic encephalopathy should be treated with therapeutic hypothermia following immediate resuscitation • Capnography most reliable method to confirm and continually monitor tracheal tube placement in neonates with spontaneous circulation

  27. Defibrillation • AFIB cardioversion : Biphasic 120-200J Monophasic 200J. • AFlutter cardioversion/SVT: 50-100J either monophasic or biphasic. • If the initial cardioversion shock fails, providers should increase the dose in a stepwise fashion.

  28. AED Use • Children 1-8yrs, pediatric dose attenuator should be used if available. Otherwise, standard AED may be used. • Infants (1<yr) a manual defibrillator is preferred over above option.

  29. Stable monomorphic VT responds well to monophasic or biphasic synchronized shocks at 100J. • If no response to first shock, increase dose in stepwise fashion. • Polymorphic VT is unstable as an arrest rhythm and require unsynchronized shocks.

  30. V Fib • Shock 200 J every 2 minutes • CPR for 2 minutes while admin Rx • Ventilate, IV Epi, Amiodarone 300mg

  31. The Rationale • True effective dose (lower or upper limit) known but doses (4J/kg-9J/kg) have been found to have no significant adverse effects.

  32. Give Oxygen when needed • Supplementary oxygen is not needed for pts without evidence of respiratory distress or when oxyhemoglobin saturation is >93% • EMS providers administer oxygen during the initial assessment of pts with suspected ACS/ However, there is insufficient evidence to support it’s routine use in uncomplicated ACS. If the pt is dyspneic, is hypoxemic, or has obvious signs of heart failure, providers should titrate oxygen therapy to maintain O2 sat >93%

  33. Airway and Breathing • Continuous quantitative waveform capnography is now recommended for intubated pts throughout the periarrest period. Useful in confirming ETT placement and for monitoring CPR quality and detected ROSC based on end tidal CO2 values.

  34. SUMMARY • Look, listen, feel - removed • Healthcare providers briefly check for breathing when checking responsiveness to detect signs of cardiac arrest. • After delivery of 30 compressions, lone rescuers open the victim’s airway and deliver 2 breaths. • Encourage hands only CPR for untrained • “Continuous” CPR for advanced providers • Do GREAT CPR • AND C-A-B - radical but rational!

  35. CARDIAC ARREST • A few changes in emphasis…

  36. IV • “ provision of high-quality CPR and rapid defibrillation are of primary importance and drug administration is of secondary importance” • 20ml Bolus after drug

  37. IO Access • Reasonable to establish access if IV access is not readily available

  38. Emergence of Supraglottic Devices • CPR more important than airway initially • Put in a supraglottic if intubation is going to be “hard” • LMA • King LT

  39. Capnography • 100% sensitive and specific for tracheal intubation • Helps count 8-10 breaths minute • Predictor of outcome

  40. No Atropine in PEA/Asystole • “Available evidence suggests that the routine use of atropine during PEA or asystole is unlikely to have a therapeutic benefit”

  41. Drugs= Transcutaneous Pacing • It hurts! • No better than drugs • Ok to go from drugs to TV pacing • NOT ROUTINE in arrest

  42. Seek Reversible Causes • 5Hs • Hypoxia • Hypovolemia • Hyperacidosis • Hyperkalemia • Hypothemia • 5Ts • Thrombus (MI) • Thrombus (PE) • Tension PTX • Toxins • Tamponade

  43. Vasopressors • VF continues after epi and CPR - vasopressor • Amiodarone is first line • Not proven to result in long term outcome • Lidocaine is useless also

  44. Epinephrine • Never any evidence that it works! • Abstract 1: A Randomized placebo controlled trial of adrenaline in cardiac arrest- the PACA trial • Conclusion: The use of adrenaline in cardiac arrest was associated w significant increase in the proportion of pts achieving ROSC however this improvement did not extend to survival to hospital discharge. As our results are unable to rule out a clinically meaningful benefit of adrenaline in terms of survival to hospital discharge, further investigation into the post resuscitation period for those achieving ROSC is required in order to identify management strategies to improve survival.

  45. SUMMARY • Atropine OUT for PEA/Asystole • CPR first and fast • Airway- supraglottic emerges • Still have amiodarone even though it don’t work • Hope lies in a reversible cause

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