1 / 20

Viviane Dias Lima British Columbia Centre for Excellence in HIV/AIDS vlima@cfenet.ubc

British Columbia Centre for Excellence in HIV/AIDS. What can we learn from the impact of dramatically scaling-up treatment on future costs and prevention efforts?. Viviane Dias Lima British Columbia Centre for Excellence in HIV/AIDS vlima@cfenet.ubc.ca.

padma
Télécharger la présentation

Viviane Dias Lima British Columbia Centre for Excellence in HIV/AIDS vlima@cfenet.ubc

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript


  1. British Columbia Centre for Excellence in HIV/AIDS What can we learn from the impact of dramatically scaling-up treatment on future costs and prevention efforts? Viviane Dias Lima British Columbia Centre for Excellence in HIV/AIDSvlima@cfenet.ubc.ca

  2. Rationale Evidence • MTCT (De Cock 2000; Coovadia 2009) • PEP (Pinkerton 2004, Fisher 2006) • Discordant Couples (Quinn 2000; Castilla 2005; Wawer 2005; Bechange 2008; Garnett 2008) • Population-based studies (Fang 2004; Lima 2007; Anema 2009) • Mathematical Models (Blower 2000; Law 2001; Abbas 2006; Montaner 2006; Lima 2007-2009; Granich 2009; De Cock 2009) HAART stops HIV replication  HIV levels fall to undetectable in blood as well as in sexual fluids  Sharp reduction in HIV transmission

  3. Evidence from British Columbia

  4. Lima V JID 2008 Lima VD, et al. Expanded access to highly active antiretroviral therapy: a potentially powerful strategy to curb the growth of the HIV epidemic. J Infect Dis 2008; 198:59-67

  5. ex at the age of 20 years: 23.6 years Direct cost to treat each person with first-line therapy: $15,400 CAN Lima VD, et al. Expanded access to highly active antiretroviral therapy: a potentially powerful strategy to curb the growth of the HIV epidemic. J Infect Dis 2008; 198:59-67

  6. Return on increased investment resulting from status quo approach versus 50% and 75% expansion scenarios Lima V JID 2008

  7. Current global ARV need

  8. Number of people receiving antiretroviral drugs in low- and middle-income countries (2002 - 2007) UNAIDS & WHO 2008

  9. UNAIDS & WHO 2008

  10. Funding gap between resource needs and resource availability (2005-2007) Needs Availability UNAIDS & WHO 2008

  11. Effect of PEPFAR on HIV Incidence

  12. Lima 2009

  13. Where do we go next?

  14. Scaling-up ART: Needs & Constraints → Cost (direct & indirect) → Limited Resources - How to prioritize the available funds? → Treatment Guidelines - When to start? - 1st & 2nd Line Therapy? - Laboratory Monitoring → Treatment of Co-morbidities & other Health Issues → Long-term Sustainability: Health Systems & Funding → Other Concurrent Prevention Efforts → Social & Gender Inequalities →Cultural & Governmental Barriers →Human Rights Issues …

  15. Thanks!

  16. Other slides

  17. Effect of PEPFAR on HIV Incidence

  18. Lima 2009

  19. Current global ARV need

  20. UNAIDS & WHO 2008

More Related