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Concentrations of Zt/g4-DM1 ( μ g/ml)

Caption: Effect of anti-RON ADCs in vitro on reduction of viability of CRC cells expressing no or low levels of RON. Cell viability (% of control). IC 50 for LoVo ( μ g/ml) CmIgG-DM1: not reached Zt/g4-DM1: not reached Zt/c1-DM1: not reached. IC 50 for DLD1 ( μ g/ml)

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Concentrations of Zt/g4-DM1 ( μ g/ml)

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  1. Caption: Effect of anti-RON ADCs in vitro on reduction of viability of CRC cells expressing no or low levels of RON. Cell viability (% of control) IC50 for LoVo (μg/ml) CmIgG-DM1: not reached Zt/g4-DM1: not reached Zt/c1-DM1: not reached IC50 for DLD1 (μg/ml) CmIgG-DM1: not calculated Zt/g4-DM1: 20.36 Zt/c1-DM1: 21.14 Concentrations of Zt/g4-DM1 (μg/ml) Feng et al. Supplementary Fig 2:

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