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ANTACIDS

ANTACIDS. Human Stomach. Gastric juices in stomach Contain HCl ( aq ) Ph 1-3 To suppress growth of bacteria To help in digestion by hydrolysing proteins to amino acids. Indigestion. Excess acid production Abdominal discomfort after eating Over eating Stress Certain foods

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ANTACIDS

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  1. ANTACIDS

  2. Human Stomach Gastricjuices in stomach ContainHCl (aq) Ph 1-3 Tosuppressgrowth of bacteria Tohelp in digestionbyhydrolysingproteinsto amino acids

  3. Indigestion Excessacidproduction Abdominal discomfortaftereating Overeating Stress Certainfoods Acideatsawayprotective mucus layer Painfululcers

  4. Antacids Remedyforexcessstomachacidity Bases Metal oxides, hydroxides Metal carbonates Metal hydrogencarbonates (bicarbonates)

  5. Effect of Antacids Neutraliseexcessacid and adjuststomachphtodesiredlevel Stomachliningrepairsitself Active ingredients Aluminiumhydroxide Magnesiumhydroxide Sodiumhydrogen carbonate

  6. Alginates Combinedwithantacids Extractedfrombrownseaweeds Produce a neutralisinglayerrthatpreventsacidreflux E.g. theypreventacidfromrisingintooesophagus «Heartburn»

  7. Dimethicone Anti-foamingagent Addedto reduce surfacetension of gas bubbles Causes bubblestocoalesce (come together) Produces defoamingaction

  8. Sideeffects Aluminiumhydroxidemay cause constipation Can preventuptake of phosphateions (precipitation of aluminiumphosphate) Largechargetosizedensity leads tobindingwithotherdrugs

  9. SideEffects Magnesiumhydroxide has laxativeproperties Calcium carbonate may lead tokidneystones Sodiumionsmay lead tohypertension

  10. Alkalosis Takingtoomuchantacid leads toalkalosis (a rise in ph of blood) Also can lead toexcessiveamounts of calciumions in body

  11. Question Twosolidantacidproductscontainsamemass of different active ingredients. Onecontainssodiumbicarbonate, theothercalcium carbonate. Whichisthebetterbuy and why ?

  12. To Do Look at active ingredients of antacidson page 410 Also look at chemicalequations Then try question 3 on page 434

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