GLYCERENE

1. GLYCERENE

2. Glycerene Reduces metabolic problems, improves fertility and increases milk yield

3. Cost of Metabolic diseases • Displaced abomasum £750 (Kingshay 2011) • Ketosis £81 (Cornell University) • Retained placenta £274 (Esslemont 1997) • Metritis £220 (Georgia University) • Poor fertility efficiency linked to incidences of metabolic problems

4. Why do we have metabolic problems? • High genetic merit cows depleting reserves • Insufficient energy supply • Rapid weight loss • Fat mobilisation • Suppression of the immune system

5. Periods 1 2 3 4 5 Body Stores Used for Milk Production Body Stores Regained for Next Lactation Dry Period Rumen Rehab Freshening 1 2 3 4 5 6 9 11 0 7 8 10 12 Month Nutrient and Milk Yield Relationships in the Lactation and Gestation Cycle Dry Matter Intake Milk Production BodyWeight

6. Measuring weight loss and fat mobilisation • Body condition – useful aid but poor system for pre calvers and fresh as damage done by the time noticed • High butterfat % in early lactation – a guide to an indication of problems • NEFA’s – fastest and scientifically accurate through blood testing • NEFA’s are Non-Esterified Fatty Acids – a measure of rapid weight loss

7. NEFA Thresholds • Trial to link NEFA levels with severity of metabolic problems (Cornell University, 2009) • 2758 cows blood sampled 15 days pre partum and 15 days postpartum • Risk ratios calculated on NEFA levels – how likely an occurrence of metabolic disease

8. Cornell Results

9. How do we reduce NEFA’s? • Increase dry matter intake both pre partum and postpartum • correct dry matter • barrier space • housing • feed quality • water • management • Feed GLYCERENE

10. Condition Change Post Calving

11. Trials • R Kupczynski, Wroclaw, Poland, 2011

12. Trials • R Kupczynski, Wroclaw, Poland, 2011

13. Trials • R Kupczynski, Wroclaw, Poland, 2011

14. Trials

15. Trials • Y H Chung, Penn State University, 2007 • Urine ketones lower with glycerine (6.8 vs 17.9) • NEFA’s lower • Milk yield same for 21 days, but at 42 days was 6 litres higher (52 litres vs. 46 litres) • “Cows receiving glycerine were in a better metabolic state than cows receiving no glycerine”

16. UK Trial Wiltshire Average days Pre Calving: Control 10, Glycerene 6 Average days Post Calving: Control 20, Glycerene 18 Glycerene fed cows were under more stress from being closer to calving and post calving than the control. Since using Glycerene, this herd has reduced metabolic problems by 80%

17. Summary • Energy deficiency results in rapid weight loss • Best measurement by NEFA’s • Metabolic diseases linked to poor fertility • Metabolic diseases very costly • Reducing NEFA’s reduces metabolic problems Glycerene reduces NEFA’s

18. More glycerine uses • Dynamite (nitro glycerine) • Skin moisturisers • Antiseptic (mouth wash, cough medicine, toothpaste) • Moisturising agent for cereal bars, icing • Kills harmful bacteria • Preserves foods • Sweetener

19. Glycerine in human food

20. What is GLYCERENE? • Glycerine on a dry base – more even mixing; easier to handle. Trials show the dry product more effective. • Unique treatment process – reduces up to 35% losses in the mouth and throat. • Palatable – tastes sweet • Reduces moulds and heating – used in mixes for keeping TMR cool

21. Financial BenefitsRef: Cornell University 2009 • High NEFA cows gave 650kgs less milk • High NEFA cows 14-18% less likely to conceive • 650kgs milk = £162.00 (25p/litre) • 14% = 50 days on calving index = £250/cow • TOTAL cost of £412/cow with high NEFA’s • Glycerene fed 21days pre & 150 days post calving costs £42/cow • Benefit of £370/cow

22. GLYCERENE Benefit of £370/Cow