1 / 26

Allergy and Hypersensitivity

0. Allergy and Hypersensitivity. K. J. Goodrum 2006. 0. Types of Immune Hypersensitivity Reactions. 0. Types of Immune Hypersensitivity Reactions. 0. Properties of Inhaled Allergens. 0. Penetration of epithelial Barriers by Allergens. 0.

rolf
Télécharger la présentation

Allergy and Hypersensitivity

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript


  1. 0 Allergy and Hypersensitivity K. J. Goodrum 2006

  2. 0 Types of Immune Hypersensitivity Reactions

  3. 0 Types of Immune Hypersensitivity Reactions

  4. 0 Properties of Inhaled Allergens

  5. 0 Penetration of epithelial Barriers by Allergens

  6. 0 Early IL-4 response promotes Th2 development that drives B cell class switching to IgE

  7. 0 Signaling through Stat6 is necessary for Th2 responses. Th2 cells support IgE responses.

  8. 0 Antigen binding to IgE on mast cells leads to amplification of IgE production

  9. 0 Mast cell activation affects many tissues

  10. 0 Molecules released upon activation of mast cells

  11. 0 Molecules released upon activation of mast cells

  12. 0 Toxic granule proteins and inflammatory substances released upon activation of eosinophils

  13. 0 Toxic granule proteins and inflammatory substances released upon activation of eosinophils

  14. 0 Acute vs. late phase inflammatory responses

  15. 0 TH2 mediated chronic inflammation in Asthma

  16. Treatment approaches for IgE-mediated Allergy 0

  17. Type II Cytotoxic reaction 0

  18. 0 Immune Complex mediated local inflammation such as in Arthus Reaction

  19. 0 Serum Sickness: an Immune complex disease

  20. 0

  21. 0 Type IV Hypersensitivity Reactions

  22. 0 Stages of a Type IV Hypersensitivity Reaction

  23. 0 Th1 derived cytokines and chemokines direct Type IV reactions

  24. 0 Allergic Contact Dermatitis: A type IV reaction

  25. 0 Blistering skin lesions on hand of patient with poison ivy contact dermatitis (a type IV reaction)

  26. 0 Granulomatous inflammation is a consequence of chronic Type IV reactions

More Related