ESMEC - European School of Medicinal Chemistry

1. ESMEC - European School of Medicinal Chemistry SUNDAY JULY 4 15.00 - 18.30 Registration 19.00 – 22.00 Poster Exhibition and Buffet Dinner

2. EUROPEAN SCHOOL OF MEDICINAL CHEMISTRY MONDAY, JULY 5 9.00 – 9.20 Opening of ESMEC 2010 Federico DA SETTIMO – President of the Medicinal Chemistry Division of the Italian Chemical Society Peter MATYUS - Chair of Education and Training Committee of EFMC Gloria CRISTALLI – Director of European PhD School of Medicinal Chemistry Infection Diseases: Focus on AIDS and Flu Chairperson: Antonello MAI - University “La Sapienza”, Roma (I) 9.20 – 9.30 Introduction to the Session 9.30 – 10.15 Christophe PANNECOUQUE, Institute for Medical Research, Leuven (B) 10.15 – 11.00 Maria Josè CAMARASA, Institute de Quimica Medica, Madrid, (E) “Small-Molecules as Inhibitors of HIV-1 Reverse Transcriptase. From Nucleosides to Peptides” 11.00 – 11.30 Coffee Break 11.30 – 12.15 Kristof VAN EMELEN , Tibotec Research and Development, Mechelen, (B) “HIV-from Killer Disease to Sleeping Enemy?” 12.15 – 13.00Andrea SAVARINO, Italian National Institute of Health, Roma (I) “Developing Strategies for HIV-1 Eradication” 13.30 – 14.30 Lunch 14.30 – 15.15 Poster session 1 Chairperson: Maria PAPPALARDO - University of Catania (I) 15.15 – 16.00 Paul SCHNITZLER, Department of Infectious Diseases-Virology, University Hospital, Heidelberg (D) “Perspective on Swine Flu: Pathology and Therapy” 16,00 – 16,45 Anna Teresa PALAMARA , University “La Sapienza”, Roma (I) “Flu: Pathology and Therapy. An Updated Perspective” 20.30 Dinner

3. EUROPEAN SCHOOL OF MEDICINAL CHEMISTRY TUESDAY, JULY 6 Drug Delivery to the Targets Chairperson: Roberta FRUTTERO- University of Torino (I) 9.00- 9.15 Introduction to the Session 9.15 - 10.00 Ronit SATCHI-FAINARO, Sackler School of Medicine,University of Tel Aviv (IL) “Rational Design of Multifunctional Polymer Therapeutics Targeting Cancer” 10.00 - 10.45 Paolo CALICETI, Department of Pharmaceutical Sciences, University of Padova (I) “Targeting and Delivery of Antitumoral Drugs” 10.45 - 11.15 Coffee Break 11.15 - 12.00 Stephen HANESSIAN, Department of Chemistry, University Montreal , Canada (CDN) “Strategies toward Tumor-Directed Chemoterapeutic Agents” 12.00 - 13.30 Poster session 2 Chairperson: - Cosimo ALTOMARE University of Bari (I) 13.30 - 15.00 Lunch 15.00-15.45 Arto URTTI, Centre for Drug Research, Faculty of Pharmacy, University of Helsinki (S) “Nanoparticles in Drug Delivery” 15.45 - 17.45 Workshop 20.30 Dinner

4. EUROPEAN SCHOOL OF MEDICINAL CHEMISTRY WEDNESDAY, JULY 7 Challenges in the Synthesis of Bioactive Compounds Chairperson: Carlo DE MICHELI- University of Milano (I) 9.00 – 9.15 Introduction to the Session 9.15 – 10.00 Stephen HANESSIAN, Department of Chemistry, University Montreal , Canada (CDN) “Structure- Based Organic Synthesis: from Natural Products to Drug Prototypes” 10.00 – 10.45 Luciana AUZZAS, Istituto di Chimica Biomolecolare, CNR, Sassari (I) “Designing Mimetics of Protein-Peptide Interactions: Natural Tools and Synthetic Strategies” 10.45 – 11.15 Coffee Break 11.15 – 12.00 Ian BAXEDALE, The Innovative Technology Centre, University of Cambridge, (UK) “Automating Synthesis through the Application of Flow Reactors” 12.00 – 12,45 Javier MAGANO, Pfzer Global Research & Development, Groton (USA) “Challenges in Process Chemistry: Design and Implementation of Scalable, Cost-Efficient and Green Routes for the Manufacture of Pharmaceuticals” 12.45 – 15.00 Lunch 15.00 – 15,45 Matteo ZANDA, Institute of Medical Sciences, University of Aberdeen (UK) “Fluorine Chemistry in Positron Emission Tomography (PET) Imaging” 15.45 – 18.00 Workshop 20.30 Dinner

5. EUROPEAN SCHOOL OF MEDICINAL CHEMISTRY THURSDAY, JULY 8 Hot Topics Chairperson: Maria Novella ROMANELLI - University of Florence (I) 9.00 - 9,15 Introduction to the Session 9.15 – 10.00 Klaus MULLER, Pharmaceutical Research, F-Hoffmann-La Roche, Basel (CH) “Fluorine in Pharmaceuticals: Intuition and Design” 10.00 – 10.45 Vipul PATEL, The Medicine Research Centre, GSK, Stevenage (UK) “Fragment Based Approach in Modern Drug Discovery” 10.45 – 11.15 Coffee break 11.15 – 12.00 Javier ROJO, Instituto de Investigaciones Quimicas, University of Sevilla (E) “Dendrimers as Therapeutic Agents against Viral Infections” 12.00 – 12.45 Paolo PEVARELLO - Newron Pharmaceuticals, Bresso, MI (I) “Drugs Approved By EMEA and FDA in 2009 (To Market! To market!)” 12.45 – 14.45 Lunch 14.45 – 18.00 Presentation and Discussion of Selected Posters Chairperson: Giorgio TARZIA - University of Urbino 18.00 Concluding Remarks Gloria CRISTALLI - University of Camerino (I) ESMEC Director 20.30 Gala Dinner

6. EUROPEAN SCHOOL OF MEDICINAL CHEMISTRY FRIDAY, JULY 9 Leaving of Partecipants