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Al 2010 mgm - PowerPoint PPT Presentation

Disorders of Cholesterol Homeostasis

Disorders of Cholesterol Homeostasis. Niemann-Pick disease, type C. Autosomal recessive, progressive, lethal, neurodegenerative disorder due to mutation of either NPC1 or NPC2 Endolysosomal storage of unesterified cholesterol and lipids Incidence: 1/100,000-120,000

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Disorders of Cholesterol Homeostasis