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DNA REPAIR

DNA REPAIR

BIOCHEMISTRY

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646 views • 49 slides
The Mutability and Repair of DNA

The Mutability and Repair of DNA

The Mutability and Repair of DNA. (transition). (transversion). purine. pyrimidine. Replication errors and their repair. The nature of mutations: Point mutation. 1. Switch of one base for another:. 2. insertion or deletion of a nucleotide. Drastic changes in DNA. Deletion Insertion

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560 views • 23 slides
Base Excision and DNA Binding Activities of Human Alkyladenine DNA Glycosylase

Base Excision and DNA Binding Activities of Human Alkyladenine DNA Glycosylase

Base Excision and DNA Binding Activities of Human Alkyladenine DNA Glycosylase Are Sensitive to the Base Paired with a Lesion. Abner, C., Lau, A., Ellenberger, T., and Bloom, L. (2001) J. Biol. Chem. 276, 13379-13387. Background. Types of DNA Mutations (spontaneous and/or induced)

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279 views • 15 slides
Announcements

Announcements

Announcements. Exam 3 is next Wednesday, 3/28 Material for Exam 3: Lectures 19-25 Topics: DNA replication, transcription, RNA processing, translation, cancer, DNA damage and DNA repair (assigned reading from Chaps. 11, 14, 15, 16) Key terms #7-8 Homeworks 5-7

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179 views • 11 slides
Base Excision Repair

Base Excision Repair

Base Excision Repair. Base Excision Repair (BER). Nature, 411:366-374, 2001.

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252 views • 2 slides
Conclusions

Conclusions

SPECIFIC INHIBITION OF THE REDOX ACTIVITY OF THE MULTIFUNCTIONAL APE1/REF-1 PROTEIN BY E3330 BLOCKS TNF- a -INDUCED ACTIVATION OF IL-8 PRODUCTION IN HEPATIC CELL LINES E. Codarin 1 , L. Cesaratto 1,2 , A. Caragnano 1 , S. Bellentani 2,3 *, M.R. Kelley 4 , C. Tiribelli 2 , G. Tell 1 .

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154 views • 1 slides

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