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B cell effector functions II Overview of antibody response and changes in antibodies

B cell effector functions II Overview of antibody response and changes in antibodies

B cell effector functions II Overview of antibody response and changes in antibodies Antibody class switching -brief review of effector functions Class switching mechanism- part 1 overview and targeting -distinction from V(D)J recombination

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613 views • 52 slides
Primary Immunodeficiencies

Primary Immunodeficiencies

Primary Immunodeficiencies. Heterogenous group of rare, single-gene diseases leading to impairment of the immune responses Inherited as X-linked or autosomal disorders, either dominant or recessive

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575 views • 43 slides
Antibodies

Antibodies

Antibodies. Secreted by B lymphocytes Great diversity and specificity: >10 9 different antibodies; can distinguish between very similar molecules Tag particles for clearance/destruction Protect against re-infection (vaccines). Antibody Structure.

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827 views • 42 slides
B lymphocyte-mediate recognition of antigens and the immune response

B lymphocyte-mediate recognition of antigens and the immune response

B lymphocyte-mediate recognition of antigens and the immune response. Contents. B cell-mediate immune response to T-dependent antigen B cell-mediate immune response to T-independent antigen The general rule of humoral immune response. Humoral immunity:

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644 views • 36 slides
Aims

Aims

Aims. Humoral immune response. primary and secondary antibody responses. T cell-dependent and T cell-independent antigens and the antibody response to each. Effector functions of antibodies including neutralization and ADCC. Readings: Abbas & Lichtman, Chapter 7 & 8. Humoral Response.

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354 views • 35 slides

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