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Outline

Outline

Outline. Matched pairs Non-central hypergeometric distribution Test for no association: McNemar test Estimating the odds ratio Conditional MLE Mantel-Haenszel estimate Confidence interval 1:M matching fixed number of controls per case Conditional MLE Mantel-Haenszel estimate

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736 views • 43 slides
Linkage Analysis: An Introduction

Linkage Analysis: An Introduction

Linkage Analysis: An Introduction. Pak Sham Twin Workshop 2001. Linkage Mapping. Compares inheritance pattern of trait with the inheritance pattern of chromosomal regions First gene-mapping in 1913 (Sturtevant) Uses naturally occurring DNA variation (polymorphisms) as genetic markers

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650 views • 33 slides
Linkage Analysis: An Introduction

Linkage Analysis: An Introduction

Linkage Analysis: An Introduction. Pak Sham Twin Workshop 2001. Linkage Mapping. Compares inheritance pattern of trait with the inheritance pattern of chromosomal regions First gene-mapping in 1913 (Sturtevant) Uses naturally occurring DNA variation (polymorphisms) as genetic markers

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577 views • 33 slides
16: Odds Ratios [from case-control studies]

16: Odds Ratios [from case-control studies]

16: Odds Ratios [from case-control studies]. Case-control studies get around several limitations of cohort studies. Cohort Studies (Prior Chapter). Use incidences to assess risk Exposed cohort ? incidence 1 Non-exposed cohort ? incidence 0 Compare incidences via risk ratio (?).

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908 views • 28 slides
Twinning

Twinning

Twinning. Finish absolute configuration Non-merohedral twinning Merohedral twinning. How can a cell be enantiomorphic if the contents are racemic?. For non-polar accentric cells the contents are completely racemic yet the unit cell is enanitomorphic.

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827 views • 27 slides

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