'Patterson map' diaporamas de présentation

Structural Genomics aims in identifying as many new folds as possible.

1.17k views • 91 slides

Interpreting difference Patterson Maps in Lab this week!

Interpreting difference Patterson Maps in Lab this week!. Calculate an isomorphous difference Patterson Map (native-heavy atom) for each derivative data set. We collected12 derivative data sets in lab (different heavy atoms at different concentrations) HgCl 2 PCMBS Hg(Acetate) 2 EuCl 3

731 views • 46 slides

Patterson Space and Heavy Atom Isomorphous Replacement

Patterson Space and Heavy Atom Isomorphous Replacement. MIR = Multiple heavy atom Isomorphous Replacement phasing. SIR = Single heavy atom Isomorphous Replacement phasing. Amplitudes for a 2 atom crystal.

487 views • 40 slides

Molecular Biophysics Solving the phase problem

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Molecular Replacement

Molecular Replacement. Phases may be calculated given a known structure. R. R. R. R. molecular replacement. If the structure of the molecule is known approximately, then the phases can be calculated. BUT. We need to know how the molecule is oriented. R. R. R. R.

402 views • 22 slides