'Pdgf receptor' diaporamas de présentation

Liyan Xu

Oncogene Cancer suppressive gene. Liyan Xu. The basic concept 1 oncogene: These genes code for proteins that are capable of stimulating cell growth and division . In normal tissues and organisms, such growth-stimulating proteins are regulated, so that growth is appropriately limited.

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Perturbation of Signal Transduction

-. -. 1. 2. 1. 3. 2. 3. Perturbation of Signal Transduction Pathways for Growth Factors and Growth Inhibitors in Malignant Transformation. Ligand isoform. Extra- cellular. TM. Intra- cellular. Receptor type. Different isoforms of PDGF form three types of receptor dimers. PDGF-CC.

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236 views • 23 slides

PDGF- ? Receptor

PDGF- ? Receptor. Chris Halloran 03.04.2004. Baker, http://www.bcm.tmc.edu/medicine/hema-onco/lectures/mds/sld017.htm. PDGF- ? Receptor Function. Receptor Tyrosine Kinase Activated by PDGF ligand dimers. Lodish et al. Fig. 20-21. PDGFR Ligands. http://www.licr.org/07_spot/PDGF.htm.

256 views • 14 slides