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History of PK-PD: 1970s- 2008: From the Formative Years to Mainstream Use

History of PK-PD: 1970s- 2008: From the Formative Years to Mainstream Use

History of PK-PD: 1970s- 2008: From the Formative Years to Mainstream Use. Michael N. Dudley, Pharm. D, FIDSA. Senior Vice President, Research and Development and Chief Scientific Officer San Diego, CA. Four Decades of PK-PD: 1970-2008. What were the key tools? Analytical Models Drugs

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527 views • 39 slides
INTERESTING CASE ROUNDS

INTERESTING CASE ROUNDS

INTERESTING CASE ROUNDS. Alyssa Morris Emergency Medicine R3. Objectives. DDX for toxin induced seizures DDX for toxin induced status epilepticus Indications for pyridoxine Review methylxanthine toxicity Review MDAC. CASE. 19M took an unknown ingestion and had a seizure.

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507 views • 30 slides
Three Compartment Model

Three Compartment Model

Three Compartment Model. Remifentanil vs. other opioids. 100. 10. Percent of peak plasma opioid concentration. fentanyl. 1. sufentanil. alfentanil. remifentanil. 0.1. 360. 480. 600. 240. 0. 120. Minutes since bolus injection. Minto et al, Anesthesiology, in press.

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1.49k views • 21 slides
PART 2: QIN PET Phantom Segmentation Challenge

PART 2: QIN PET Phantom Segmentation Challenge

PART 2: QIN PET Phantom Segmentation Challenge. Instructions. Goals for Part 2. Perform segmentations and analysis on the UI and UW PET phantom volumes Volumes and activities are known Two repeat segmentations/measurements for all data sets!.

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183 views • 8 slides
-10000

-10000

4000. 2000. 0. 1. 2. 4. 8. 12. 0. T max (h). -2000. Predicted AUC 0-24 - Observed AUC 0-24 (ngh/mL). -4000. r = -0.164 P = 0.276. -6000. -8000. -10000.

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105 views • 1 slides

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