'Peptide natriuretic peptides functioning' diaporamas de présentation

Peptide synthesis technology with great potential

Peptide synthesis is a solid phase synthesis process generally from the n-terminal (amino terminal) to the c-terminal (carboxyl terminal) synthesis. In the past it was carried out in solution called liquid phase synthesis. in 1963, Merrifield proposed solid-phase peptide synthesis (SPPS). The process of synthesis was convenient, rapid so that it became the preferred method and brought about a revolution of the peptides in organic synthesis. Afterwards through continuous improvement and efforts, today solid-phase method has become a common technique in peptide and protein synthesis while showing unparalleled advantages compared with the classic liquid phase synthesis. For example, greatly reducing the difficulty of purifying product in each step.

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